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https://journals.physiology.org/doi/full/10.1152/ajpheart.2001.280.6.h2591
According to Poiseuille's law, an increase in blood viscosity should result in a lowered blood flow to the brain resulting in decreased cerebral oxygen delivery. The unchanged cerebral blood flow (CBF) at an increased blood viscosity ( 2 , 25 ) indicates a compensatory vasodilation that keeps cerebral oxygen transport constant.
https://www.ncbi.nlm.nih.gov/pubmed/11356614
Oxygen delivery at high blood viscosity and decreased arterial oxygen content to brains of conscious rats. Rebel A(1), Lenz C, Krieter H, Waschke KF, Van Ackern K, Kuschinsky W. Author information: (1)Faculty of Clinical Medicine, Department of Anesthesiology, Mannheim D-68067, Heidelberg, Germany. [email protected]: A. Rebel, C. Lenz, H. Krieter, K. F. Waschke, K. Van Ackern, W. Kuschinsky
https://ndnr.com/cardiopulmonary-medicine/blood-viscosity/
Blood viscosity is a measurement of the thickness and stickiness of a patient’s blood. This important hemodynamic biomarker determines the amount of friction against the blood vessels, the degree to which the heart must work, and the quantity of oxygen delivery to the tissues and organs.
https://grantome.com/grant/NIH/U54-HL090511-03-1
The effect of changes in blood viscosity on high and low shear flow and oxygen delivery has not been measured in humans with SCD. Goals: This project will determine the relation between prefrontal cerebral cortex oxygen delivery, cerebral arterial flow and blood viscosity and %HbS.
https://www.ahajournals.org/doi/10.1161/01.CIR.74.5.1085
It is known that blood viscosity is a determinant of resistance to blood flow at both the stenotic and the arteriolar levels. Accordingly, a reduction in blood viscosity could exert a favorable influence on maximal myocardial oxygen delivery in the setting of stenosis, provided that the oxygen-carrying capacity of the blood is not compromised excessively.Author: A S Most, N A Ruocco, H Gewirtz
https://academic.oup.com/bjaed/article/4/4/123/308019
Aug 01, 2004 · Increased oxygen extraction by the tissues occurs during anaemia by improved matching of oxygen delivery to oxygen demand. There is a redistribution of blood flow to areas of high demand, such as the myocardium and the brain. In the microcirculation a number of mechanisms help to maintain tissue oxygenation.Author: S. A. McLellan, T. S. Walsh
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2519874/
Under physiological conditions, during hemodilution with and without an artificial hemoglobin solution, in oxygen content matched groups, cerebral blood flow (CBF) was greater in animals with decreased viscosity. 9 In the brain, a 4-fold variation of blood viscosity at the same oxygenation level does not produce a change of the local CBF. 2 Thus, at reduced blood viscosity, tissue perfusion increases to maintain oxygen delivery …Author: C. Lenz, A. Rebel, K.F. Waschke, R.C. Koehler, T. Frietsch
https://www.sciencedirect.com/topics/agricultural-and-biological-sciences/blood-viscosity
RBC deformability is determined by the geometric properties, cytoplasmic composition and viscosity, and membrane properties of RBC [62]. Exercise training improves baseline RBC deformability [63,64]. Having pliable RBCs is beneficial for microcirculatory blood flow, tissue oxygen delivery and aerobic performance [63].
https://www.sciencedirect.com/topics/biochemistry-genetics-and-molecular-biology/blood-viscosity
Blood viscosity variation, primarily determined by hematocrit, results in trivial alterations in CBF in healthy subjects (hematocrit range 33%-45%). 52,53 The benefit of improved CBF resulting from reduced viscosity is more relevant in the setting of focal cerebral ischemia when vasodilation in response to impaired oxygen delivery is probably already maximal. 54,55 In the setting of focal …
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