We have collected information about Block Copolymer Micelles For Drug Delivery Design for you. Follow the links to find out details on Block Copolymer Micelles For Drug Delivery Design.
https://www.sciencedirect.com/science/article/pii/S0169409X00001241
Block copolymer micelles for drug delivery: design, characterization and biological significance ... A further challenge in the development of novel micellar carrier systems is in the design of polymeric micelles for cellular-specific targeting in which pilot-molecules are installed on their surface to achieve a specific-binding property to ...Author: Kazunori Kataoka, Atsushi Harada, Yukio Nagasaki
https://www.ncbi.nlm.nih.gov/pubmed/11251249
Mar 23, 2001 · Block copolymer micelles for drug delivery: design, characterization and biological significance. ... and biological properties is reviewed from the standpoint of designing micellar carrier systems for receptor-mediated drug delivery. Further, the distribution of polymeric micelles is described to demonstrate their long-circulating ...Author: Kazunori Kataoka, Atsushi Harada, Yukio Nagasaki
https://www.sciencedirect.com/science/article/abs/pii/S0169409X12002736
Block copolymer micelles for drug delivery: Design, ... This paper highlights the utility of polymeric micelles formed through the multimolecular assembly of block copolymers as novel core–shell typed colloidal carriers for drug and gene targeting. The process of micellization in aqueous milieu is described in detail based on differences in ...Author: Kazunori Kataoka, Atsushi Harada, Yukio Nagasaki
https://onlinelibrary.wiley.com/doi/10.1002/9781118747896.ch6
Block copolymer amphiphiles self‐assemble in aqueous solutions into micelles and vesicles. This chapter reviews the biological challenges and opportunities associated with block copolymer drug delivery vehicles and outlines their successes in the delivery of drugs and nucleic acids in vitro and in vivo. It focuses on block copolymer micelles ...Author: James D. Robertson, Nisa Patikarnmonthon, Adrian S. Joseph, Giuseppe Battaglia
https://pubs.acs.org/doi/pdf/10.1021/acs.chemrev.8b00199
imminent challenges for polymeric micelles as nanomedicines are discussed, anticipating to spur further innovations. CONTENTS 1. Introduction 6845 2. Block Copolymer Self-Assemblies for Drug Delivery 6846 3. Design Criteria of Block Copolymers for Self-Assembly of Polymeric Micelles 6848 3.1. Shell-Forming Segments 6848 3.2. Core-Forming ...
https://pubs.acs.org/doi/full/10.1021/acs.chemrev.8b00199
Polymeric micelles are demonstrating high potential as nanomedicines capable of controlling the distribution and function of loaded bioactive agents in the body, effectively overcoming biological barriers, and various formulations are engaged in intensive preclinical and clinical testing. This Review focuses on polymeric micelles assembled through multimolecular interactions between block ...Author: Horacio Cabral, Kanjiro Miyata, Kensuke Osada, Kazunori Kataoka
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4113619/
Apr 04, 2014 · Polymeric micelles represent an effective delivery system for poorly water-soluble anticancer drugs. With small size (10–100 nm) and hydrophilic shell of PEG, polymeric micelles exhibit prolonged circulation time in the blood and enhanced tumor accumulation.Author: Yifei Zhang, Yixian Huang, Song Li
https://www.researchgate.net/publication/281994054_Block_copolymer_micelles_for_drug_delivery_Design_characterization_and_biological_significance
Block copolymer micelles for drug delivery: Design, characterization and biological significance Article in Advanced Drug Delivery Reviews 109(1):169-188 · March 2001 with 73 Reads
http://www.eurekaselect.com/58294/article
Abstract: Polymeric micelles are nanoscopic core/shell structures formed by amphiphilic block copolymers. Both the inherent and modifiable properties of polymeric micelles make them particularly well suited for drug delivery purposes.
https://royalsocietypublishing.org/doi/10.1098/rsif.2008.0547.focus
In contrast to micelles from small surfactant molecules, polymeric micelles are generally more stable and can retain the loaded drug for a prolonged period of time even in a very diluted condition in the body due to appreciably lowered critical micelle concentration, particularly for polymeric micelles from highly regulated block copolymers ...Author: Kensuke Osada, R. James Christie, Kazunori Kataoka
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