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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2856328/
Aug 15, 2008 · The syntheses of phosphatidylserine (PS) conjugates are described, including fluorescent derivatives for potential cellular delivery and bioimaging applications. Installation of terminal functional groups (amine, thiol, or alkyne) onto the sn -2 chain provides reactive sites for bio-orthogonal conjugation of cargo with suitably protected PS derivatives.Author: Andrew J. Lampkins, Edward J. O’Neil, Bradley D. Smith
https://pubs.acs.org/doi/10.1021/jo8011336
The syntheses of phosphatidylserine (PS) conjugates are described, including fluorescent derivatives for potential cellular delivery and bioimaging applications. Installation of terminal functional groups (amine, thiol, or alkyne) onto the sn-2 chain provides reactive sites for bio-orthogonal conjugation of cargo with suitably protected PS derivatives.Author: Andrew J. Lampkins, Edward J. O’Neil, Bradley D. Smith
https://pubs.acs.org/doi/suppl/10.1021/jo8011336/suppl_file/jo8011336-file002.pdf
Bio-orthogonal Phosphatidylserine Conjugates for Delivery and Imaging Applications A. J. Lampkins, E. J. O’Neil, and B. D. Smith* Department of Chemistry and Biochemistry and Walther Cancer Research Center, 251 Nieuwland Science Hall, University of Notre Dame, Notre Dame, IN 46556 Email : [email protected] Table of Contents
https://www3.nd.edu/~bsmith3/pdf/JOC2008.pdf
The syntheses of phosphatidylserine (PS) conjugates are described, including fluorescent derivatives for potential cellular delivery and bioimaging applications. Installation of terminal functional groups (amine, thiol, or alkyne) onto the sn-2 chain provides reactive sites for bio-orthogonal conjugation of cargo with suitably protected PS derivatives.
https://www.researchgate.net/publication/5234878_Bio-orthogonal_Phosphatidylserine_Conjugates_for_Delivery_and_Imaging_Applications
The syntheses of phosphatidylserine (PS) conjugates are described, including fluorescent derivatives for potential cellular delivery and bioimaging applications.
https://www.sciencedirect.com/science/article/pii/S0040403918305318
In general, the biomolecule can be selectively labelled by a bioorthogonal reaction with a complementary reagent bearing a fluorescent probe or affinity handle. 1 Some bioorthogonal reactions can be further applied to animal tissue imaging, drug delivery, and biomaterials. 9 This review will highlight the most recent development of bioorthogonal reactions, especially the new progress within the recent five years, focused on the optimization on the bioorthogonal reagents …Author: Li-Huai Qin, Li-Huai Qin, Wei Hu, Ya-Qiu Long
https://pubs.acs.org/doi/full/10.1021/acscentsci.8b00251
Bioorthogonal reactions have found widespread use in applications ranging from glycan engineering to in vivo imaging. Researchers have devised numerous reactions that can be predictably performed in a biological setting.Author: Neal K. Devaraj
https://www.nature.com/articles/nchembio.2024
Feb 16, 2016 · Here we highlight the development and applications of these bioorthogonal cleavage reactions. ... detection and its application in hypoxic tumor cell imaging. ... drug conjugates…Author: Jie Li, Peng R Chen, Peng R Chen
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