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https://www.fda.gov/regulatory-information/search-fda-guidance-documents/restricted-delivery-systems-flow-restrictors-oral-liquid-drug-products-guidance-industry
Restricted Delivery Systems: Flow Restrictors for Oral Liquid Drug Products Guidance for Industry March 2020. ... Center for Biologics Evaluation and Research.
https://science.sciencemag.org/content/303/5665/1818.full
Mar 19, 2004 · Drug delivery systems (DDS) such as lipid- or polymer-based nanoparticles can be designed to improve the pharmacological and therapeutic properties of drugs administered parenterally.Author: Theresa M. Allen, Pieter R. Cullis
https://onlinelibrary.wiley.com/doi/abs/10.1002/adma.201901935
Jun 20, 2019 · Technologies in clinical trials, as well as recent and disruptive delivery systems proposed in the literature for local and systemic delivery of biologics including peptides, antibodies, and nucleic acids, are described. Strategies for the specific targeting of gastrointestinal regions—stomach, small bowel, and colon—cell populations,...Author: Matilde Durán‐Lobato, Zhigao Niu, Zhigao Niu, María José Alonso
https://www.nature.com/articles/nrd.2018.183
Nov 30, 2018 · Given the rise of peptides and proteins in the pharmaceutical landscape, tremendous research and development interest exists in developing less-invasive or non-invasive routes for the systemic delivery of biologics, including subcutaneous, transdermal, oral, …Author: Aaron C. Anselmo, Yatin Gokarn, Samir Mitragotri
https://www.nature.com/articles/aps201712
Apr 10, 2017 · Introduction In the past decade, nanoscale drug delivery systems (DDS) have attained considerable prominence 1. Various nanobased drug formulations have …Author: Xin Luan, Kanokwan Sansanaphongpricha, Ila Myers, Hongwei Chen, Hebao Yuan, Duxin Sun
https://www.researchgate.net/publication/261140729_Biologics_The_role_of_delivery_systems_in_improved_therapy
Successful performance of any controlled drug delivery system (DDS) relies on the drug elution kinetics which further depends on the degradation behavior of the biodegradable polymers.Author: Natasa Skalko-Basnet
http://www.americanpharmaceuticalreview.com/Featured-Articles/345540-Opportunities-and-Challenges-in-Biologic-Drug-Delivery/
Dec 22, 2017 · In fact, regulatory agencies are evaluating new biologics in combination with their delivery mechanisms. Thus, from process chemists to manufacturers, drug developers should be thinking about LVWI delivery early, while the biologic molecules are still in development and ahead of any scale-up. An early start will also reward formulation teams.
https://www.armstrongmedical.net/product/spirale/
Spirale® Drug Delivery system (DDS) spacer for Metered Dose Inhalers (MDI) Reduce the risk of pathogen transmission. Spirale® can help to reduce the risk of pathogen transmission. In previous outbreaks (SARS, H1N1 and MERS) the World Health Organisation highlighted that Aerosol generating procedures increased risk of pathogen transmission.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3964020/
Mar 19, 2014 · Moreover, nasal delivery is considered as an attractive route in delivery aimed at brain targeting and overcoming the blood–brain barrier.37 Intranasal delivery of large molecular weight biologics, such as proteins and gene vectors, is an attractive means to treat a variety of central nervous system disorders such as multiple sclerosis, Parkinson’s disease, epilepsy, and Alzheimer’s disease.38Author: Nataša Škalko-Basnet
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