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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4978509/
Framework of sequential biological barriers to nanoparticle drug delivery. Upon intravenous administration, drug-containing nanoparticles encounter a number of sequential obstacles hindering efficacious, site-specific delivery to tumors. Nanoparticles undergo opsonization and subsequent uptake by resident macrophages of the MPS.Author: Elvin Blanco, Haifa Shen, Haifa Shen, Mauro Ferrari, Mauro Ferrari
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2527668/
A multitude of substances are currently under investigation for the preparation of nanoparticles for drug delivery, varying from biological substances like albumin, gelatine and phospholipids for liposomes, and more substances of a chemical nature like various polymers and solid metal containing nanoparticles.Author: Wim H De Jong, Paul Ja Borm
https://jnanobiotechnology.biomedcentral.com/articles/10.1186/s12951-018-0392-8
Sep 19, 2018 · The green chemistry route of designing nanoparticles loaded with drugs is widely encouraged as it minimises the hazardous constituents in the biosynthetic process. Thus, using green nanoparticles for drug delivery can lessen the side-effects of the medications . Moreover, adjustments in nanostructures size, shape, hydrophobicity, and surface ...Author: Jayanta Kumar Patra, Gitishree Das, Leonardo Fernandes Fraceto, Leonardo Fernandes Fraceto, Estefani...
https://www.sciencedirect.com/science/article/pii/S1319016417301792
An ideal nanoparticle drug delivery system should be able to reach, recognized, bind and deliver its load to specific pathologic tissues, and minimize or avoids drug induced damage to healthy tissues.Thus, coating specific targeting ligand(s) on the surface of nanoparticles is the most common strategy.Author: Syed A.A. Rizvi, Ayman M. Saleh
https://www.intechopen.com/books/nanomedicines/silver-nanoparticles-as-multi-functional-drug-delivery-systems
Nanoparticles can surmount some essential problems of conventional small molecules or biomacromolecules (e.g., DNA, RNA, and protein) used in some diseases by allowing targeted delivery and overcome through biological barriers. Recently, silver nanoparticles have been harnessed as delivery vehicles for therapeutic agents, including antisense oligonucleotides, and other small …Author: Nadezhda Ivanova, Viliana Gugleva, Mirena Dobreva, IvayloPehlivanov, Stefan Stefanov, Velichka Andon...
https://www.nature.com/articles/nbt.3330
Sep 08, 2015 · Mauro Ferrari and colleagues discuss the biological barriers to delivery of nanoparticle therapeutics to diseased tissues. They propose that greater …Author: Elvin Blanco, Haifa Shen, Haifa Shen, Mauro Ferrari, Mauro Ferrari
https://www.sciencedirect.com/science/article/pii/S014181302032746X
In the present work, attempts were made to modify these nanoparticles suitable for drug delivery applications. Since particle size has a crucial role for drug delivery application, the preparation method was modified with the application of probe sonication.
https://www.nature.com/articles/aps201712
Apr 10, 2017 · Engineering exosomes as refined biological nanoplatforms for drug delivery. ... Copper-free azide-alkyne cycloaddition of targeting peptides to porous silicon nanoparticles for intracellular drug ...Author: Xin Luan, Kanokwan Sansanaphongpricha, Ila Myers, Hongwei Chen, Hebao Yuan, Duxin Sun
https://www.researchgate.net/publication/286931813_Gold_NanoparticlesA_Boon_to_Drug_Delivery_System
Gold Nanoparticles:A Boon to Drug Delivery System. ... Gold nanoparticles: a bo on to drug delivery system. ... Nanotechnology applied to biological problems represents an emerging field with the ...
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