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https://www.bio-rad.com/en-us/category/biolistic-particle-delivery-systems?ID=09facf6d-b7a7-490a-bb87-9326aa5309e1
The Helios gene gun is a convenient handheld device that provides direct, rapid, and versatile gene delivery into a range of targets in vivo. PDS-1000 He™ and Hepta™ Systems The PDS-1000/He system uses a burst of high-pressure helium gas to accelerate nucleic acid–coated gold or tungsten microparticles to velocities necessary to transfect cells, tissues, or organelles.
https://www.bio-rad.com/webroot/web/pdf/lsr/literature/Bulletin_5443.pdf
Biolistic technology has been applied to targets as diverse as chloroplasts, mitochondria, bacteria, fungi, algae, and pollen. The Helios gene gun has been used to further our understanding of cancer, infectious disease, and wound healing; to generate immune responses in animals; and to assay gene expression and regulation both in vivo and in vitro.
https://www.biotecharticles.com/Others-Article/What-is-Biolistics-522.html
The two commonly used gene delivery systems are agrobacterium and biolistics. However host-range specificity is a biological barrier when agrobacterium is used for transformation purposes. This can be overcome by using particle bombardment techniques. An example is the ease of transformation of papaya tree using biolistics.
https://www.sciencedirect.com/topics/neuroscience/biolistic-transformation
Biolistics is based on the direct delivery of DNA into plant cells using gold or tungsten particles. 80 The gold or tungsten particles are coated with DNA which are shot at plant tissue at high velocity and can become lodged inside plant cells. Once inside the cell, the DNA elutes off the particles and becomes transiently expressed or stably integrates into the host genome.
https://msu.edu/course/css/451/Lecture/WK2-PT-Biolistic(2009).pdf
Using a gene gun directly shoots a piece of DNA into the recipient plant tissue. Tungsten or gold beads are coated in the gene of interest and fired through a stopping screen, accelerated by Helium, into the plant tissue. The particles pass through the plant cells, leaving the DNA inside. Gene Delivery System-----Biolistic-mediated transformationFile Size: 1MB
https://angelaweiling.weebly.com/advantage-and-disadvantage-of-biolistic.html
Large DNA fragments may be transferred as well as small interfering RNA's for gene silencing; Many cells types can be transfected, including non-dividing cells and plants; Potentially toxic treatments such as using viruses or chemical are avoided
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3725258/
Transient gene expression is a useful approach for studying the functions of gene products. In the case of plants, Agrobacterium infiltration is a method of choice for transient introduction of genes for many species. However, this technique does not work efficiently in some species, such as Arabidopsis thaliana.Author: Shoko Ueki, Shimpei Magori, Benoît Lacroix, Vitaly Citovsky
https://www.sciencedirect.com/topics/biochemistry-genetics-and-molecular-biology/gene-gun
Gene-gun delivery, a handheld form of biolistic system used for DNA vaccination since the 1990s (Williams et al., 1991), consists of propelling DNA-coated colloidal gold microprojectiles toward the tissue surface. Gas-accelerated particles penetrate into deeper …
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3507026/
Jul 06, 2012 · Actually it is a modification of a technique called “biolistic,” originally developed for plant transgenesis, but now used for in vitro and in vivo gene delivery into mammalian cells too,[89,90] such as skin, mucosa, or surgically exposed tissue and especially for DNA-based immunization or vaccination.
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