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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2952648/
Aug 16, 2010 · For specific cancer-targeted drug delivery, the intracellular integration and drug-delivery efficiency of F-FMSNs were compared to those of FMSNs. The effect of folic acid conjugation on the cellular uptake of nanoparticles was examined with a breast cancer cell, SK-BR-3, …Author: Jie Lu, Monty Liong, Zongxi Li, Jeffrey I. Zink, Fuyuhiko Tamanoi
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2663893/
Aug 04, 2008 · Introduction. Nanoparticles have drawn increasing interest from every branch of medicine 1–5 for their ability to deliver drugs in the optimum dosage range, often resulting in increased therapeutic efficacy of the drug, weakened side effects, 6,7 and improved patient compliance. Today, there are several examples of nontargeted NPs currently used in clinical practice (Doxil 8–11 and ...Author: Frank Alexis, Eric Pridgen, Linda K. Molnar, Omid C. Farokhzad
https://www.sciencedirect.com/science/article/pii/S0731708512003408
Biodistribution of nanoparticles: Initial considerations ... and the use of nanoparticles as drug-delivery systems. ... Thus, all nanoparticles should make the biodistribution test in animal models in order to improve the information about these behavior and the possible consequences in human model.Author: Lucas Torres Miranda Sa, Marta de Souza Albernaz, Beatriz Ferreira de Carvalho Patricio, Mario Ville...
https://pubs.acs.org/doi/abs/10.1021/mp800049w
Jul 09, 2008 · Chemical and physical properties of the nanoparticles, including size, surface charge, and surface chemistry, are important factors that determine their PK and biodistribution. The intracellular fate of the nanoparticles after cellular internalization that affects the drug bioavailability is also discussed.Author: Shyh Dar Li, Shyh Dar Li, Leaf Huang
https://www.researchgate.net/publication/304706414_Factors_Affecting_the_Pharmacokinetics_Biodistribution_and_Toxicity_of_Gold_Nanoparticles_in_Drug_Delivery
Factors Affecting the Pharmacokinetics, Biodistribution and Toxicity of Gold Nanoparticles in Drug Delivery Article in Current Drug Metabolism 17(9) · June 2016 with 206 Reads How we measure 'reads'
https://www.sciencedirect.com/science/article/pii/B9780081005576000092
The tailoring of the nanoparticles is a tool to achieve better drug delivery and desired pharmacokinetics (Hans and Lowman, 2002, Han et al., 2007). Cheng et al. employed PEG and polyacrylic acid to formulate the coated functionalized nanoparticles and reported the enhanced blood circulation half-life.Author: Kaisar Raza, Pramod Kumar, Nitesh Kumar, Ruchi Malik
http://if-pan.krakow.pl/pjp/pdf/2012/5_1020.pdf
by limited effectiveness, poor biodistribution, and lack of selectivity [111]. These limitations and draw-backs can be overcome by controlling drug delivery. In controlled drug delivery systems (DDS) the drug is transported to the place of action, thus, its influence on vital …
https://jnanobiotechnology.biomedcentral.com/articles/10.1186/s12951-018-0392-8
Sep 19, 2018 · The green chemistry route of designing nanoparticles loaded with drugs is widely encouraged as it minimises the hazardous constituents in the biosynthetic process. Thus, using green nanoparticles for drug delivery can lessen the side-effects of the medications . Moreover, adjustments in nanostructures size, shape, hydrophobicity, and surface ...Author: Jayanta Kumar Patra, Gitishree Das, Leonardo Fernandes Fraceto, Leonardo Fernandes Fraceto, Estefani...
https://www.researchgate.net/publication/319704115_The_effect_of_particle_shape_on_cellular_interaction_and_drug_delivery_applications_of_micro-_and_nanoparticles
The apparent impact of particle shape inspired the new research in the field of drug delivery. The present review therefore details the research in this field. ... Biodistribution of nanoparticles ...Author: Anil Jindal
https://www.nature.com/articles/nrd4333
Oct 07, 2014 · Multifunctional and stimulus-sensitive nanoparticles can overcome issues associated with traditional drug delivery by, for example, improving targeting and bioavailability. Here, Torchilin ...Author: Vladimir P. Torchilin, Vladimir P. Torchilin
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