We have collected information about Biodegradable Polymers Drug Delivery Systems for you. Follow the links to find out details on Biodegradable Polymers Drug Delivery Systems.
https://www.sciencedirect.com/science/article/pii/B9781845690700500047
A defining therapeutic feature of a biodegradable polymer used in modern drug delivery is facile degradation into oligomers or monomers with concomitant kinetically controlled-drug-release profiles. Biodegradable drug carriers are responsible for delivering drugs and then typically degrading through hydrolysis or common proteases for physiological clearance.Author: G. S. Kwon, D. Y. Furgeson
https://biomedres.us/fulltexts/BJSTR.MS.ID.002056.php
One example of a successful polymeric drug delivery system is Norplant, an implantable contraceptive device. It was oneof the first drug delivery systems to be widely used in clinical practice. However, it is a non-degradable system and therefore requires surgical removal once the drug has depleted.Author: Kiran Dhaliwal, Priya Dosanjh, Jose Sanchez Payá
https://www.researchgate.net/publication/279724491_Biodegradable_Polymers_as_Drug_Delivery_Systems
However, the monomer chain of PCL has five hydrophobic hydrocarbons in line, which increase the hydrophobicity of the polymer when compared to PLAs and PGAs, changing it to become slowly biodegradable ( Kwon and Furgeson 2007, Henton et al., 2005, Kohn and Langer 1996).
https://www.pharmatutor.org/articles/biodegradable-polymers-role-drug-delivery
The use of biodegradable polymer in drug delivery grew from the search for polymers that could be employed as degradable sutures. Synthetic polymers such as poly (glycolic acid) were first developed in the 1950is and their poor hydrolytic stability made them unsuitable for permanent applications.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3438887/
The majority of responsive polymers for drug delivery can be broadly categorized as hydrogels, micelles, polyplexes, or polymer-drug conjugates, which are covered in more detail below. Hydrogels are hydrophilic (co)polymeric networks capable of imbibing …Author: William B. Liechty, David R. Kryscio, Brandon V. Slaughter, Nicholas A. Peppas
https://jnanobiotechnology.biomedcentral.com/articles/10.1186/s12951-020-00609-2
The optimal drug delivery system should be biocompatible, biodegradable, and allow the sustained release of the drug only after it reaches the target cells. Silk, as a natural polymer, is a great candidate for building drug carriers. Genetically engineered silks offer the possibility of functionalization.
https://www.sciencedirect.com/science/article/pii/S1226086X19302060
Natural biodegradable polymers as vaccine adjuvants and delivery systems Natural biopolymers have attracted attention as controlled delivery systems for peptide, protein, and DNA Ags. In addition to chitosan, protein assemblies and other naturally occurring biopolymers, such as β-glucans, dextran, and mannan, have been proposed for different ...Author: Rajendran Jc Bose, Rajendran Jc Bose, Minwoo Kim, Ji Hyun Chang, Ramasamy Paulmurugan, James J. Moon...
https://www.researchgate.net/publication/299126177_Biodegradable_polymer_microspheres_as_vaccine_adjuvants_and_delivery_systems
Biodegradable polymer microspheres as vaccine adjuvants and delivery systems Conference Paper (PDF Available) in Developments in biologicals · January 1998 with 191 Reads How we measure 'reads'
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6032388/
May 23, 2018 · Choice of the polymer depends on the properties of the system, such as therapeutic application of the formulation, the targeted drug-release profile, biocompatibility, etc. Namely, for the vaginal route, polymers able to meet to the different conditions of the cavity, such as pH changes, mucoadhesivity, ease of mucous penetration, stability in ...Author: Gerardo Leyva-Gómez, Elizabeth Piñón-Segundo, Néstor Mendoza-Muñoz, María L. Zambrano-Zaragoza, Susa...
https://www.mdpi.com/2227-9717/7/7/396/htm
Compatibility between drugs and polymers concerns not only the miscibility but also the extent of interaction with no alteration in the chemical structure neither the polymer or the drug [].A good interaction (physisorption) between drug and delivery hydrogel/polymers is the first step in the design of drug delivery systems; however, no delivery carrier prepared from a particular polymer will ...Author: Eliceo Cortes, Edgar Márquez, José R. Mora, Esneyder Puello, Norma Rangel, Aldemar De Moya, Jorge Tr...
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