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https://www.researchgate.net/publication/299126177_Biodegradable_polymer_microspheres_as_vaccine_adjuvants_and_delivery_systems
Biodegradable polymer microspheres as vaccine adjuvants and delivery systems Conference Paper (PDF Available) in Developments in biologicals · January 1998 with 191 Reads How we measure 'reads'
https://www.researchgate.net/publication/51342903_Biodegradable_polymer_microspheres_as_vaccine_adjuvants_and_delivery_systems
Biodegradable polymer microspheres as vaccine adjuvants and delivery systems. Article · Literature Review (PDF Available) in Developments in biological standardization 92:63-78 · January 1998 ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4514183/
Microsphere-based systems, providing controlled release delivery, can obviate the need for repeat immunizations. Here, we review the function of sustained and pulsatile release of biodegradable polymeric microspheres in parenteral and mucosal single-dose vaccine administration. We also review the active-targeting function of polymeric particles.Author: Chi-Ying Lin, Shih-Jie Lin, Yi-Chen Yang, Der-Yuan Wang, Hwei-Fang Cheng, Ming-Kung Yeh
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3465129/
VACCINE DELIVERY SYSTEMS. Delivery of antigens from oil-based adjuvants such as Freunds[] adjuvant lead to a reduction in the number of doses of vaccine to be administered but due to toxicity concerns like inductions of granulomas at the injection site, such adjuvants are not widely used.FDA approved adjuvants for human uses are aluminium hydroxide and aluminium phosphate in the form of …
https://link.springer.com/chapter/10.1007%2F12_2011_150
Oct 20, 2011 · Abstract. Polymeric nano- and microparticles have recently been shown to possess significant potential as drug delivery systems. In particular, the use of biodegradable polymeric nanoparticles with entrapped antigens such as proteins, peptides, or DNA represents an exciting approach for controlling the release of vaccine antigens and optimizing the desired immune response …Author: Takami Akagi, Masanori Baba, Mitsuru Akashi
https://www.sciencedirect.com/science/article/pii/S0927776509004111
Biodegradable polymeric nanoparticles based drug delivery systems. ... Careful design of these delivery systems with respect to target and route of administration may solve some of the problems faced by new classes of active molecules. ... Biodegradable polymeric nanoparticles are highly preferred because they show promise in drug delivery system.Author: Avnesh Kumari, Sudesh Kumar Yadav, Subhash Chandra Yadav
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