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https://www.sciencedirect.com/science/article/pii/S0168365900003394
Over the past few decades, there has been considerable interest in developing biodegradable nanoparticles (NPs) as effective drug delivery devices. Various polymers have been used in drug delivery research as they can effectively deliver the drug to a target site and thus increase the therapeutic benefit, while minimizing side effects [1] .Author: Kumaresh S Soppimath, Tejraj M Aminabhavi, Anandrao R Kulkarni, Walter E Rudzinski
https://www.sciencedirect.com/science/article/abs/pii/S0168365900003394
This review presents the most outstanding contributions in the field of biodegradable polymeric nanoparticles used as drug delivery systems. Methods of preparation, drug loading and drug release are covered. The most important findings on surface modification methods as well as surface characterization are covered from 1990 through mid-2000.Author: Kumaresh S Soppimath, Tejraj M Aminabhavi, Anandrao R Kulkarni, Walter E Rudzinski
https://www.researchgate.net/publication/222571527_Biodegradable_Polymeric_Nanoparticles_as_Drug_Delivery_Devices
Nanoparticles (NPs) based on biocompatible and biodegradable polymers such as poly(lactic-co-glycolic acid) (PLGA) and polycaprolactone (PCL) represent effective systems for systemic drug delivery.
https://www.sciencedirect.com/science/article/pii/S1359028602001171
Because of their versatility and wide range of properties, biodegradable polymeric nanoparticles are being used as novel drug delivery systems. In particular, this class of carrier holds tremendous promise in the areas of cancer therapy and controlled delivery of vaccines.Author: M.L Hans, A.M Lowman
https://www.sciencedirect.com/science/article/pii/S0927776509004111
Biodegradable nanoparticles have been used frequently as drug delivery vehicles due to its grand bioavailability, better encapsulation, control release and less toxic properties. Various nanoparticulate systems, general synthesis and encapsulation process, control release and improvement of therapeutic value of nanoencapsulated drugs are covered in this review.Author: Avnesh Kumari, Sudesh Kumar Yadav, Subhash Chandra Yadav
https://en.wikipedia.org/wiki/Nanoparticles_for_drug_delivery_to_the_brain
Nanoparticles made from natural polymers that are biodegradable have the abilities to target specific organs and tissues in the body, to carry DNA for gene therapy, and to deliver larger molecules such as proteins, peptides, and even genes. To manufacture these polymeric nanoparticles, the drug molecules are first dissolved and then encapsulated or attached to a polymer nanoparticle matrix.
https://www.sciencedirect.com/science/article/pii/S0014305719305920
For attaining sustained and controlled drug delivery, these polymers are modified to develop drug carriers such as nanoparticles, microparticles, microspheres, and matrix devices etc. This review explains the use of biodegradable polymers and their drug delivery systems for local or targeted and controlled/sustained drug/gene delivery.Author: Shiv Kumar Prajapati, Ankit Jain, Aakanchha Jain, Sourabh Jain
https://www.mdpi.com/2079-4991/10/4/720/htm
Ocular inflammation is one of the most prevalent diseases in ophthalmology, which can affect various parts of the eye or the surrounding tissues. Non-steroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen, are commonly used to treat ocular inflammation in the form of eye-drops. However, their bioavailability in ocular tissues is very low (less than 5%). Therefore, drug delivery systems ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3238292/
Nov 28, 2011 · AM's lab is developing biodegradable nanoparticles for gene and drug delivery and is also participating in a collaborative project with DKS' lab on the use of biodegradable nanoparticles in delivering a HIV- DNA vaccine within the cervical and vaginal mucosa. DKS: is an associate professor of microbiology at the Winston Salem State University.Author: Anil Mahapatro, Dinesh K Singh
https://www.intechopen.com/books/application-of-nanotechnology-in-drug-delivery/polymer-nanoparticles-for-smart-drug-delivery
Recently, the polymeric nanoparticles have emerged as a most promising and viable technology platform for recognizing the targeted, environment-responsive and, multi-functional with navigated controlled drug delivery system. Polymer in smart drug delivery is a rapid-emerging new technological discipline in which various therapeutic applications ...Author: Devasier Bennet, Sanghyo Kim
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