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https://link.springer.com/referenceworkentry/10.1007%2F978-3-319-76573-0_47-1
Jun 22, 2018 · Hence the author has made an attempt to discuss biodegradable polymers of natural and synthetic origin, the biodegradation mechanisms, hydrogel engineering strategies, drug-hydrogel interactions, and release kinetics and mechanisms of such hydrogels to attain controlled delivery of drugs to different site of action in this chapter.
https://www.sciencedirect.com/science/article/pii/S1359644616302562
Hydrogel-based drug delivery systems can be more efficacious than the systemic therapies. They provide a high concentration and a sustained release of the drugs at tumor site. Thermo-, pH-, photo- and dual-sensitive hydrogels can be used for local drug delivery.Author: Mohammad Norouzi, Bahareh Nazari, Donald W. Miller
https://www.sciencedirect.com/science/article/pii/S0378517308008570
In the swelling assays, the hydrogels based on pachyman exhibited significant pH sensitivity, while the hydrogels based on hydroxyethyl pachyman tended to have notable swelling capability. In the drug release study, two drugs salicylic acid and bovine serum albumin (BSA) were chosen as model drugs.Author: Yan Hu, Xiaoju Zhou, Yong Lu, Chengyang Hu, Xianming Hu
http://publications.waset.org/13806/design-a-biodegradable-hydrogel-for-drug-delivery-system
Furthermore, the swelling of superabsorbing hydrogels was examined in solutions with pH values ranging between 1.0 and 13.0. It showed a reversible pH-responsive behavior at pHs 2.0 and 8.0. This on-off switching behavior makes the synthesized hydrogels as an excellent candidate for controlled delivery of bioactive agents.
https://www.sciencedirect.com/science/article/pii/S0141813019337377
However, dextran-based conductive hydrogel with electrical stimuli responsiveness as drug delivery system has not been reported. Herein, we designed and fabricated a kind of biocompatible biodegradable conductive hydrogel system with the property of electro-responsiveness as a new smart drug delivery system for localized drug release.Author: Jin Qu, Yongping Liang, Mengting Shi, Baolin Guo, Yanzheng Gao, Zhanhai Yin
https://link.springer.com/article/10.1007%2Fs10965-019-1771-z
May 03, 2019 · Kinetic models further suggested a first order release rate, indicating that the release is primarily mediated by diffusion through porous membranes of the hydrogel. Such hydrogel based drug delivery system promises an effective strategy for sustaining drug release for the treatment of diseases.Author: Pratikkumar Patel, Abhirup Mandal, Vrinda Gote, Dhananjay Pal, Ashim K. Mitra
https://www.sciencedirect.com/science/article/pii/S0927776509004111
Encapsulation of diabetes drugs (insulin) on PCL nanoparticles. Nanoparticles prepared with a blend of a biodegradable polyester PCL and a poly cationic non-biodegradable acrylic polymer have been used as a drug carrier for oral administration of insulin [26]. The rate of …Author: Avnesh Kumari, Sudesh Kumar Yadav, Subhash Chandra Yadav
https://www.researchgate.net/publication/230785490_Hydrogels_as_potential_drug_delivery_systems
Hydrogels, the swellable polymeric materials, have been widely investigated as the carrier for drug delivery systems. These biomaterials have gained attention owing to their peculiar characteristics like swelling in aqueous medium, pH and temperature sensitivity or sensitivity towards other stimuli.
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