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https://www.sciencedirect.com/science/article/pii/014296129090023J
Bioadhesive polymers in peptide drug delivery David Harris and Joseph R. Robinson School of Pharmacy, University of Wisconsin-Madison, 425 North Charter Street, Madison, W I 53706, USA (Received 23 March 1990; revised and accepted 21 May 1990) A frequently encountered problem with the peptide-based drugs which are becoming available is that these agents must generally be …Author: David Harris, Joseph R. Robinson
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4287299/
Nov 15, 2014 · To date, most research into oral peptide delivery has taken place in discovery and preclinical development. The characterization and stability testing for oral peptide formulations described in the scientific literature reflects the requirements in terms of duration and rigor for this stage of research and development (69,71,72,78). As more ...Author: Annette Bak, Dennis Leung, Stephanie E. Barrett, Seth Forster, Ellen C. Minnihan, Andrew W. Leithead...
https://www.sciencedirect.com/science/article/pii/S0378517303000875
Nasal cavity as a site for systemic drug delivery has been investigated extensively and many nasal formulations have already reached commercial status including leutinising hormone releasing hormone (LHRH) and calcitonin (Illum, 1999). Chitosan and starch are the two most widely employed bioadhesive polymers for nasal drug delivery.Author: Jaspreet Kaur Vasir, Kaustubh Tambwekar, Sanjay Garg
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3255397/
In recent years, many such mucoadhesive drug delivery systems have been developed for oral, buccal, nasal, rectal and vaginal routes for both systemic and local effects. Dosage forms designed for mucoadhesive drug delivery should be small and flexible enough to be acceptable for patients and should not cause irritation.
https://link.springer.com/article/10.1023%2FA%3A1016418523014
Jul 01, 2002 · L. Illum. Bioadhesive formulations for nasal peptide delivery. In E. Mathowitz, C. M. Lehr, and D. Chickering (eds). Bioadhesion in Drug Delivery-Issues in Fundamentals, novel approaches and development, Marcel Dekker, 1998 pp 507-539.Author: A. M. Dyer, M. Hinchcliffe, P. Watts, J. Castile, I. Jabbal-Gill, R. Nankervis, A. Smith, L. Illum
https://books.google.com/books/about/Bioadhesive_Drug_Delivery_Systems.html?id=d8-Eo7iGOTkC
Amply referenced with over 1400 bibliographic citations, and illustrated with more than 300 drawings, photographs, tables, and display equations, Bioadhesive Drug Delivery Systems serves as a sound basis for innovation in bioadhesive systems and an excellent introduction to the subject.5/5(1)
https://hungary.pure.elsevier.com/hu/publications/sodium-hyaluronate-as-a-mucoadhesive-component-in-nasal-formulati
May 01, 2009 · Because of the rapid mucociliary clearance in the nasal cavity, bioadhesive formulations are needed for effective targeting. Our goal was to develop a formulation containing sodium hyaluronate, a well-known mucoadhesive molecule, in combination with a non-ionic surfactant to enhance the delivery of hydrophilic compounds to the brain via the ...Author: Sándor Horvát, Sándor Horvát, András Fehér, Hartwig Wolburg, Péter Sipos, Szilvia Veszelka, Andrea T...
https://www.researchgate.net/publication/263709483_Formulation_strategies_to_improve_oral_peptide_delivery
The most widely studied oral peptide formulations target delivery of therapeutics for diabetes, osteoporosis and to a lesser extent, acromegaly. In 2013, 382 million people
https://www.researchgate.net/publication/277742763_A_review_on_factors_affecting_the_design_of_nasal_drug_delivery_system
A review on factors affecting the design of nasal drug delivery system Article (PDF Available) in International Journal of Drug Delivery 3(2) · October 2011 with 2,420 Reads How we measure 'reads'
https://www.ondrugdelivery.com/review-oral-peptide-delivery/
Figure 1: Table summarising selected oral peptide delivery technologies. MERRION’S GIPET ® TECHNOLOGY. Merrion Pharmaceuticals (Dublin, Ireland) is developing the GIPET® technology using an enteric coating (similar to Peptelligence ® and TPE technologies), in order to protect the peptide in the acidic gastric medium and ensure peptide release in the small intestine.
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