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https://www.ncbi.nlm.nih.gov/pubmed/20619379
Aug 16, 2010 · BGs are devoid of cytoplasmic content and possess all bacterial bio-adhesive surface properties in their original state while not posing any infectious threat. BGs are ideally suited as an advanced drug delivery system (ADDS) for toxic substances in tumor therapy.Author: Pavol Kudela, Verena Juliana Koller, Werner Lubitz
https://www.sciencedirect.com/science/article/pii/S0264410X1000928X
Aug 16, 2010 · The bacterial ghost (BG) system developed during the past few years represents a new platform in vaccine development . BGs, empty bacterial shells of Gram-negative bacteria, have been developed as a novel potent carrier and adjuvant system for the delivery of DNA vaccines , , , , . BGs are produced by protein E-mediated lysis of Gram-negative bacteria.Author: Pavol Kudela, Verena Juliana Koller, Werner Lubitz
https://www.sciencedirect.com/science/article/pii/S0168165611001738
Bacterial Ghosts as antigen and drug delivery system for ocular surface diseases: Effective internalization of Bacterial Ghosts by human conjunctival epithelial cells Author links open overlay panel Pavol Kudela a c d Verena Juliana Koller a c Ulrike Beate Mayr c Johannes Nepp a Werner Lubitz c e Talin Barisani-Asenbauer a b fAuthor: Pavol Kudela, Pavol Kudela, Verena Juliana Koller, Ulrike Beate Mayr, Johannes Nepp, Werner Lubitz, ...
https://www.researchgate.net/publication/45148482_Bacterial_ghosts_BGs-Advanced_antigen_and_drug_delivery_system
Bacterial ghosts (BGs) represent empty bacterial cell envelopes of Gram-negative bacteria developed as a novel carrier for DNA, antigen (Ag), enzymes, drugs and adjuvant system for the delivery …
https://www.sciencedirect.com/science/article/pii/S0958166904001429
The bacterial ghost system represents a platform technology for antigen, nucleic acid and drug delivery. Bacterial ghosts have significant advantages over other engineered biological delivery particles, owing to their intrinsic cellular and tissue tropic abilities, ease of production and the fact that they can be stored and processed without the need for refrigeration.Author: Chakameh Azimpour Tabrizi, Petra Walcher, Ulrike Beate Mayr, Thomas Stiedl, Matthias Binder, John Mc...
https://www.researchgate.net/publication/51059415_Bacterial_Ghosts_as_antigen_and_drug_delivery_system_for_ocular_surface_diseases_Effective_internalization_of_Bacterial_Ghosts_by_human_conjunctival_epithelial_cells
Bacterial ghosts are emerging drug delivery platform that are capable of delivery of proteins, antigens, nucleic acids, and pharmaceuticals. Bacterial ghosts are generally produced by lysis of...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3037582/
The Bacterial Ghost (BG) platform technology is an innovative system for vaccine, drug or active substance delivery and for technical applications in white biotechnology. BGs are cell envelopes derived from Gram-negative bacteria. BGs are devoid of all cytoplasmic content but have a preserved cellular morphology including all cell surface structures.
https://veterinaryresearch.biomedcentral.com/articles/10.1186/s13567-017-0442-5
Jun 24, 2017 · The BG platform is a novel antigen delivery system endowed with intrinsic adjuvant properties. The native and foreign antigens can be expressed on the surface of ghosts before E-mediated lysis [78], and thus multiple antigens including bacterial, viral, etc. can be presented to the immune system simultaneously.Author: Irshad A. Hajam, Pervaiz A. Dar, Gayeon Won, John Hwa Lee
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3944611/
Bacterial ghosts are emerging drug delivery platform that are capable of delivery of proteins, antigens, nucleic acids, and pharmaceuticals. Bacterial ghosts are generally produced by lysis of gram-negative bacteria.
https://www.researchgate.net/publication/304368351_Use_of_Bacterial_Ghosts_as_Novel_Drug_Delivery_Systems_to_Improve_Cancer_Treatment
Recombinant bacterial ghosts loaded with plasmids were tested as an antigen delivery system and as a potential mediator of maturation for human monocyte-derived dendritic cells (DCs).
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