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https://www.annualreviews.org/doi/10.1146/annurev.genet.42.110807.091449
The contact-dependent growth inhibition system (CDI) is a Type V system, using a long β-helical cell surface protein to contact receptors in target cells and deliver a growth inhibitory signal. Type VI systems utilize a phage-like tube and cell puncturing device to secrete effector proteins into both eukaryotic and prokaryotic target cells.Author: Christopher S. Hayes, Stephanie K. Aoki, David A. Low
https://www.researchgate.net/publication/47675163_Bacterial_Contact-Dependent_Delivery_Systems
Bacterial Contact-Dependent Delivery Systems Article · Literature Review (PDF Available) in Annual Review of Genetics 44(1):71-90 · December 2010 with 583 Reads How we measure 'reads'
https://www.researchgate.net/profile/Christopher_Hayes/publication/47675163_Bacterial_Contact-Dependent_Delivery_Systems/links/02e7e5190e00149a39000000.pdf
GE44CH04-Low ARI 7 October 2010 9:48 Bacterial Contact-Dependent Delivery Systems Christopher S. Hayes, Stephanie K. Aoki, and David A. Low Department of Molecular, Cellular, and Developmental ...
http://www.nature.com/articles/nature09490
Nov 17, 2010 · Contact-dependent growth inhibition (CDI), first described in Escherichia coli five years ago, is a mechanism by which cell-to-cell contact inhibits the growth of bacterial cells that do not have ...Author: Stephanie K. Aoki, Elie J. Diner, Claire T.Kint De Roodenbeke, Brandt R. Burgess, Stephen J. Poole, ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3904093/
Bacterial contact-dependent growth inhibition (CDI) is mediated by the CdiA/CdiB family of two-partner secretion proteins. CDI + cells bind to susceptible target bacteria and deliver a toxic effector domain derived from the carboxyl terminus of CdiA (CdiA-CT). More than 60 distinct CdiA-CT sequence types have been identified, and all CDI toxins characterized thus far display RNase, DNase, or ...Author: Christopher S. Hayes, Sanna Koskiniemi, Zachary C. Ruhe, Stephen J. Poole, David A. Low
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3058911/
Nov 18, 2010 · A widespread family of polymorphic contact-dependent toxin delivery systems in bacteria. ... Bioinformatic and experimental analyses show that multiple bacterial species encode functional CDI systems with high sequence variability in the CdiA-CT and CdiI coding regions. CdiA-CT heterogeneity implies that a range of toxic activities are utilized ...Author: Stephanie K. Aoki, Elie J. Diner, Claire T.Kint De Roodenbeke, Brandt R. Burgess, Stephen J. Poole, ...
https://www.deepdyve.com/lp/annual-reviews/bacterial-contact-dependent-delivery-systems-0X1PWXXpyF
Dec 01, 2010 · Bacterial Contact-Dependent Delivery Systems Bacterial Contact-Dependent Delivery Systems Hayes, Christopher S.; Aoki, Stephanie K.; Low, David A. 2010-12-01 00:00:00 Bacteria have developed remarkable systems that sense neighboring target cells upon contact and initiate a series of events that enhance their survival and growth at the expense of the target cells.
https://www.cell.com/trends/microbiology/fulltext/S0966-842X(13)00023-1
May 01, 2013 · Bacteria cooperate to form multicellular communities and compete against one another for environmental resources. Here, we review recent advances in the understanding of bacterial competition mediated by contact-dependent growth inhibition (CDI) systems. Different CDI+ bacteria deploy a variety of toxins to inhibit neighboring cells and protect themselves from autoinhibition by …Author: Zachary C. Ruhe, David A. Low, Christopher S. Hayes
https://www.sciencedirect.com/science/article/pii/S1369527417301467
Specificity associated with toxin delivery, or lack thereof, may provide insights into the biological roles of bacterial contact-dependent toxin delivery systems. In general, T6SSs do not appear to require specific target cell receptors for effector translocation, instead relying on physical force to disrupt the target cell outer membrane ...Author: Erin C Garcia
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