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https://www.sciencedirect.com/science/article/pii/S0958166904001429
This review will focus on current strategies for antigen, nucleic acid and drug delivery by biological particles with an emphasis on the use of bacterial ghosts as delivery systems. Non-bacterial delivery systems. Various non-bacterial biological delivery systems are listed in Box 2. Of these, live attenuated or inactivated viruses and virus ...Author: Chakameh Azimpour Tabrizi, Petra Walcher, Ulrike Beate Mayr, Thomas Stiedl, Matthias Binder, John Mc...
https://www.ncbi.nlm.nih.gov/pubmed/9382741
Bacterial antigen delivery systems: phagocytic processing of bacterial antigens for MHC-I and MHC-II presentation to T cells. Svensson M(1), Pfeifer J, Stockinger B, Wick MJ. Author information: (1)Dept. of Cell and Molecular Biology, Lund University, Sweden.Author: Svensson M, Pfeifer J, Stockinger B, Wick Mj
https://www.sciencedirect.com/topics/medicine-and-dentistry/bacterial-antigen
Attenuated Bacterial Antigen Delivery Systems 1234. Bacterial Vector Components of RABV Antigen Delivery Systems 1234. Introduction 1234. Impact of Route of Immunization 1234. Desired Attributes 1235. Consequences of Attenuating Mutations on Vaccine Attributes 1237. Consequences of Synthesis of Protective Antigens 1238
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3465129/
VACCINE DELIVERY SYSTEMS. Delivery of antigens from oil-based adjuvants such as Freunds[] adjuvant lead to a reduction in the number of doses of vaccine to be administered but due to toxicity concerns like inductions of granulomas at the injection site, such adjuvants are not widely used.FDA approved adjuvants for human uses are aluminium hydroxide and aluminium phosphate in the form of …
https://veterinaryresearch.biomedcentral.com/articles/10.1186/s13567-017-0442-5
Jun 24, 2017 · Bacterial ghosts (BG) represent a potential platform which not only acts as potent candidate vaccines but also provide a tool for efficient adjuvant and vaccine delivery systems. This novel approach has produced promising results to curb infectious diseases, tested both in natural hosts as well as in experimental animals (Table 1).Author: Irshad A. Hajam, Pervaiz A. Dar, Gayeon Won, John Hwa Lee
https://www.cambridge.org/core/journals/expert-reviews-in-molecular-medicine/article/intracellular-delivery-of-biologic-therapeutics-by-bacterial-secretion-systems/38E0CB06CD4CA6AA6BC70F2EAAE79CB2
In this review, we provide a brief overview of the different bacterial systems capable of direct delivery into the eukaryotic cytoplasm and the medical applications for which they are being investigated, along with a perspective on the future directions of this exciting field.
https://asu.pure.elsevier.com/en/publications/antigen-delivery-systems-ii-development-of-live-recombinant-atten
The development of safe, efficacious recombinant attenuated bacterial antigen delivery systems requires attention to some desired attributes. The vaccine design should be focused on-enhancing immunogenicity and the magnitude and duration of the immune response to the expressed protective antigen, and on diminishing the potentially competing immune responses to antigens of the attenuated ...Author: Roy Curtiss
https://www.researchgate.net/publication/304368351_Use_of_Bacterial_Ghosts_as_Novel_Drug_Delivery_Systems_to_Improve_Cancer_Treatment
The bacterial ghost system represents a platform technology for antigen, nucleic acid and drug delivery. Bacterial ghosts have significant advantages over other engineered biological delivery ...
https://www.liebertpub.com/doi/10.1089/oli.1.2000.10.391
Attenuated bacterial strains allow the administration of recombinant vaccines via the mucosal surfaces. Whereas attenuated bacteria are generally engineered to express heterologous antigens, a novel approach employs intracellular bacteria for the delivery of eukaryotic antigen expression vectors (so-called DNA vaccines).Author: Guido Dietrich, Simone Spreng, Ivaylo Gentschev, Werner Goebel
https://www.researchgate.net/publication/12587888_Novel_bacterial_systems_for_the_delivery_of_recombinant_protein_or_DNA
Novel bacterial systems for the delivery of recombinant protein or DNA Article in FEMS Immunology & Medical Microbiology 27(4):299-304 · May 2000 with 33 Reads How we measure 'reads'
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