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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3038673/
This work introduced a minimally invasive strategy for drug delivery to the back of the eye. It showed that a hollow microneedle can inject liquid solution and suspensions of particles into the suprachoroidal space of rabbit, pig, and human eyes ex vivo. Suprachoroidal delivery represents an improvement over current periocular and intravitreal ...Author: Samirkumar R. Patel, Angela S. P. Lin, Henry F. Edelhauser, Mark R. Prausnitz
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2895432/
May 01, 2010 · Ocular drug delivery has been a major challenge to pharmacologists and drug delivery scientists due to its unique anatomy and physiology. Static barriers (different layers of cornea, sclera, and retina including blood aqueous and blood–retinal barriers), dynamic barriers (choroidal and conjunctival blood flow, lymphatic clearance, and tear dilution), and efflux pumps in conjunction pose a ...Author: Ripal Gaudana, Hari Krishna Ananthula, Ashwin Parenky, Ashim K. Mitra
http://www.eyecenter.emory.edu/press_releases/pr_faculty_31.htm
(ATLANTA) A new textbook, Drug Product Development for the Back of the Eye (aapspress/Springer), edited by Emory Eye Center researcher Henry F. Edelhauser, PhD and Uday B. Kompella, PhD, of the University of Colorado, explores approaches for a delivery system to get drugs to the back of the eye. In the past, drug delivery was typically systemic ...
https://medicalxpress.com/news/2019-10-advance-drug-eluting-contact-lenses-delivery.html
Oct 02, 2019 · Drug-eluting contact lenses, which gradually release drugs into the eye, offer a promising alternative to daily eye drops, which can be unpleasant and hard for patients to properly administer. In ...
https://medicalxpress.com/news/2012-01-startup-million-drug-delivery-eye.html
Jan 05, 2012 · Startup receives $4 million to develop drug delivery targeted to the back of the eye by Emory University This is researcher Samir Patel with an example of the ocular microneedle device.
https://www.fiercepharma.com/drug-delivery/all-eyes-on-psivida-for-back-of-eye-drug-delivery
Jul 05, 2011 · pSivida is getting more and more attention these days as a drug-delivery company to watch, especially as it develops products for a potentially huge market- …
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