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https://www.webmd.com/a-to-z-guides/tylenol-acetaminophen-poisoning#:~:text=Acetaminophen%20%28Tylenol%29%20Poisoning%20Overview.%20However%2C%20if%20taken%20in,recommended%20dose%20is%203%20grams%20in%2024%20hours.
https://www.bluelight.org/xf/threads/max-apap-you-have-ingested-over-24-hours-at-once.780736/
I've taken a lot in the past (probably around 9000mg or so in a 24 hour period). Very dangerous and I'm not proud of it. I weigh around 300lbs though so that may be a factor on how I was able to tolerate it without having a major OD experience. Glad I'm not on APAP combo medicines anymore so the temptation to take a lot isn't there anymore.
https://www.ncbi.nlm.nih.gov/books/NBK537183/
The oral protocol requires checking at 24 hours. If APAP is undetectable and transaminase levels are normal, NAC can be discontinued at the end of the regime. If there is a detectable APAP level or AST is still elevated, restarting NAC at 6.25 mg/kg per hour (for IV protocol) or 70 mg/kg every four hours (for oral protocol) is the proper course.
https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=a30388fa-0d85-4eb3-babd-228170ebe96d
The maximum daily dose of this product is 6 caplets (3,000 mg) in 24 hours. Severe liver damage may occur if you take. more than 4,000 mg of acetaminophen in 24 hours. with other drugs containing acetaminophen. 3 or more …
https://www.drugs.com/dosage/acetaminophen.html
Weight: 27.3 to 32.6 kg (9 to 10 years): 400 mg orally every 4 hours as needed not to exceed 5 doses in 24 hours. Weight: 32.7 to 43.2 kg (11 to 12 years): 480 mg orally every 4 hours as needed not to exceed 5 doses in 24 hours. AGE: 12 years or older: Immediate-release: 325 mg to 1 g orally every 4 to 6 hours.
https://www.childrenscolorado.org/globalassets/healthcare-professionals/clinical-pathways/acetaminophen-apap-toxicity.pdf
an 8 hour timeframe • Presenting less than 24 hours after a known time of ingestion. NONACUTE . Acetaminophen (APAP) ingestion: • Inaccurate timeline (poor history) • Unknown timeline • Repeated Supratherapeutic Ingestion (all the ingestion occurs in greater than an 8 hour timeframe) •Presenting greater than 24 hours after acute ingestion
https://www.webmd.com/sleep-disorders/sleep-apnea/sleep-apap-overview
An APAP machine may help you improve your sleep if you suffer from sleep apnea. Learn the differences between Automatic Positive Airway Pressure machines and if it's best for you.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4913076/
The United States FDA clearly states “severe liver damage may occur if you take more than 4000 mg of acetaminophen in 24 hours.”31In these extreme circumstances, prompt medical assessment and therapeutic intervention is necessary to administer therapy that will allow for salvage of a damaged and/or failing liver.
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