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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6294059/
Dec 11, 2018 · Atherosclerosis represents one of the biggest health care and societal challenges worldwide, 1, 2 but despite intensive efforts, little clinical success has been achieved in terms of targeted drug delivery nanosystems for the disease therapy. 3 To allow a better control of nanoparticle biodistribution and to enhance their therapeutic efficacy, active targeting is required.Author: Jasmin Matuszak, Barbara Lutz, Aleksander Sekita, Jan Zaloga, Christoph Alexiou, Stefan Lyer, Iwona ...
https://www.ncbi.nlm.nih.gov/pubmed/16051539
DXM-liposomes were prepared with egg yolk phosphatidylcholine, cholesterol and dicetylphosphate in a lipid molar ratio of 7/2/1 by the hydration method and then adjusted to three different particle sizes to clarify the influence of particle size on the drug delivery to atherosclerotic lesions and the effect on atherosclerosis.Author: Sumio Chono, Yoshihiko Tauchi, Yoshiharu Deguchi, Kazuhiro Morimoto
https://www.webmd.com/cholesterol-management/medications-to-treat-atherosclerosis
Drugs to Reduce High Blood Pressure. Lowering blood pressure lowers the risk of atherosclerosis and its complications. Diet and exercise alone don't usually bring high blood pressure down to the safe range. Most people with high blood pressure will require medications (usually at least two) to do the job.
https://onlinelibrary.wiley.com/doi/abs/10.1002/ddr.21103
Drugs for primary and secondary prevention of atherosclerosis and in particular its complications, e.g., myocardial infarction, are widely used therapeutics. However, those drugs typically act nonspecifically, thus affecting not only target cells and atherosclerotic lesions but also causing unwanted side effects.Author: Erik Westein, Ulrike Flierl, Christoph E. Hagemeyer, Karlheinz Peter
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6160774/
Sep 09, 2018 · These SV40-based nanoparticles were a suitable theranostic platform for in vivo optical imaging, molecular targeting, and drug delivery in atherosclerosis 109. In another theranostic example, gold nanostars conjugated to the drug mitoxantrone (MTX) were used for SERS of cancer cells, and for delivery of the antitumoral drug, which had shown a nonspecific anti-inflammatory effect for patients …Author: Julian Bejarano, Mario Navarro-Marquez, Francisco Morales-Zavala, Javier O. Morales, Javier O. Moral...
https://www.sciencedirect.com/science/article/pii/S0914508717300928
On the other hand, incorporation into MPS itself is one of the intended mechanisms of drug delivery, especially when treating inflammatory disease, such as atherosclerosis. Several studies have employed this mechanism for imaging and treatment of atherosclerosis, targeting inflammatory monocytes/macrophages in atherosclerosis.Author: Tetsuya Matoba, Jun ichiro Koga, Kaku Nakano, Kensuke Egashira, Hiroyuki Tsutsui
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