We have collected information about Atelocollagen Sirna Delivery for you. Follow the links to find out details on Atelocollagen Sirna Delivery.
https://www.sciencedirect.com/topics/medicine-and-dentistry/atelocollagen
To increase the efficiency of siRNA delivery in vivo (the main limitation of this procedure), we recommend using atelocollagen. The combination of atelocollagen and HPLC-purified siRNA allows an efficient silencing of gene expression in vivo. In the case of subcutaneous tumor xenografts, the mixture of atelocollagen and siRNA can be injected ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC506824/
Jul 22, 2004 · Atelocollagen-mediated synthetic small interfering RNA delivery for effective gene silencing in vitro and in vivo. Yoshiko Minakuchi, Fumitaka Takeshita, 1 Nobuyoshi Kosaka, 2 Hideo Sasaki, 1 Yusuke Yamamoto, 2 Makiko Kouno, 3 Kimi Honma, 3 Shunji Nagahara, ... Atelocollagen-based delivery of siRNA into cells.Author: Yoshiko Minakuchi, Fumitaka Takeshita, Nobuyoshi Kosaka, Hideo Sasaki, Yusuke Yamamoto, Makiko Kouno...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4946317/
Nov 18, 2015 · Atelocollagen-mediated siRNA delivery. Bone matrix proteins are mainly collagen, a natural biocompatible polymer with three polypeptide chains forming a helix. Atelocollagen is a highly purified pepsin-treated type I collagen of calf dermis. Under physiological conditions, atelocollagen forms a fiber-like natural collagen.Author: Xinli Liu
https://www.sciencedirect.com/topics/neuroscience/atelocollagen
Despite substantial progress in the application of atelocollagen as an siRNA delivery system, some concerns remain. Atelocollagen is soluble at temperatures below 10 °C, but solidifies above this temperature, and thus requires careful handling at room temperature (Takei et al., 2008).
https://www.future-science.com/doi/10.4155/tde.14.8
May 23, 2014 · In animal model experiments, the siRNA/atelocollagen complex that arrived at a tumor tissue downregulated the target gene expression. Accordingly, expectations are growing for the siRNA/atelocollagen complex as a novel sustained release preparation for nucleic acid-based medicine .Author: Ichiro Fujimoto, Yoshifumi Takei
https://academic.oup.com/nar/article-abstract/32/13/e109/2375748
Jan 01, 2004 · To evaluate the efficiency of Atelocollagen-mediated transfer technology using well-characterized siRNA, we employed a luciferase reporter gene system in 293 cells. As shown in Figure 3, our Atelocollagen-mediated siRNA delivery technology exhibited an inhibitory effect as efficient as that in the conventional liposome transfer method.Author: Yoshiko Minakuchi, Fumitaka Takeshita, Nobuyoshi Kosaka, Hideo Sasaki, Yusuke Yamamoto, Makiko Kouno...
https://www.liebertpub.com/doi/10.1089/nat.2014.0526
Mar 25, 2015 · Successful short interfering RNA (siRNA)-based therapy for cancers depends on functional siRNA delivery specific to tumors. In our previous report, we have shown systemic siRNA delivery specific to human prostate cancer cell line PC-3 subcutaneous tumors in nude mice by atelocollagen, a collagen derivative, for formulating a complex with siRNA.Author: YuanYuan, MakitaNaoki, CaoDongliang, MiharaKeichiro, KadomatsuKenji, TakeiYoshifumi
https://www.nature.com/articles/nm1486
Feb 25, 2007 · With the increased potential of RNA interference (RNAi) as a therapeutic strategy, new noninvasive methods for detection of siRNA delivery and silencing are urgently needed. Here we …Author: Zdravka Medarova, Wellington Pham, Christian Farrar, Victoria Petkova, Anna Moore
https://www.future-science.com/doi/pdfplus/10.4155/tde.14.8?src=recsys
Therapeutic Delivery (2014) 5(4), 369–371 ISSN 2041-5990 369 Keywords: atelocollagen • cancer • drug delivery • nucleic acid-based medicine • siRNA Drug-delivery systems for nucleic acid-based medicine In recent years, nucleic acid-based medi-cine has attracted attention for its therapeu-
Searching for Atelocollagen Sirna Delivery?
You can just click the links above. The data is collected for you.
