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https://www.sciencedirect.com/science/article/pii/0168365995000287
In addition, these asymmetric-membrane coatings can be applied to capsules and multi-particulate dosage forms. In this paper, we describe the characteristics of asym- metric-membrane tablet coatings for tablets, osmotic delivery of a drug with moderate water solubility and a drug with low water solubility,...Author: S.M. Herbig, J.R. Cardinal, R.W. Korsmeyer, K.L. Smith
https://www.sciencedirect.com/science/article/pii/S016836599800100X
The asymmetric membrane capsule is a controlled drug delivery device which consists of a drug-containing core surrounded by a membrane which has an asymmetric structure, i.e., it has a relatively thin, dense region supported on a thicker, porous region.Author: A.G Thombre, J.R Cardinal, A.R DeNoto, S.M Herbig, K.L Smith
https://www.sciencedirect.com/science/article/pii/S0378517305001857
Polymeric capsules with an asymmetric membrane wall are successfully developed for the delivery of poorly soluble drugs. In vitro release studies indicate that the drug delivery operated by osmotic effect using asymmetric membrane could be achieved with its solubility modified to a proper extent.Author: Chun Yu Wang, Hsiu O Ho, Ling Hong Lin, Ying Ku Lin, Ming Thau Sheu
https://www.researchgate.net/publication/5965184_Asymmetric_membrane_capsule_for_osmotic_delivery_of_flurbiprofen
Asymmetric membrane capsule for osmotic delivery of flurbiprofen. An asymmetric membrane capsule of cellulose acetate for osmotic delivery of flurbiprofen has been developed and influence of osmogents and solubilizing agent on in vitro drug release were evaluated. The capsule membrane was prepared by the phase inversion technique.
https://www.sciencedirect.com/science/article/pii/S0168365999000863
Other formulations of the osmotic coatings include those that consist of dense membranes containing a water-soluble ingredient which is leached out of the membrane to form the delivery ports in situ , , . Osmotic tablets with an asymmetric membrane coating which can achieve high water fluxes have also been described . The drug delivery systems described above can release the drug only as an …Author: A.G Thombre, A.R DeNoto, D.C Gibbes
https://www.sciencedirect.com/science/article/pii/S1369703X05003311
The model drug theophylline was supplied by Eczacibasi A.S. Asymmetric-membrane tablet coatings were applied using a dip coating process (Dip Coater Nima, type: D1L, serial no.: 327). Coating solutions were prepared by dissolving cellulose acetate (Aldrich) in a …Author: Sacide Alsoy Altinkaya, Hacer Yenal
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2750498/
Osmotic flow through asymmetric membrane: A means for controlled delivery of drugs with varying solubility Anil K. Philip and Kamla Pathak Department of Pharmaceutics, Rajiv Academy for Pharmacy, Delhi-Mathura Bye Pass, NH# 2, 286001 Mathura, Uttar Pradesh, IndiaAuthor: Anil K. Philip, Kamla Pathak
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3407637/
Jul 17, 2012 · Osmotic drug delivery systems typically consist of a drug core containing osmogen that is coated with a semipermeable membrane. This coating has one or more delivery ports through which a solution or suspension of the drug is released over time.Author: Rajesh A. Keraliya, Chirag Patel, Pranav Patel, Vipul Keraliya, Tejal G. Soni, Rajnikant C. Patel, M...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3513454/
A nondisintegrating, floating asymmetric membrane capsule (FAMC) was developed to achieve site-specific osmotic flow of a highly water-soluble drug, ranitidine hydrochloride (RHCl), in a controlled manner. Solubility suppression of RHCl was achieved by the common ion effect, using optimized coated sodium chloride as a formulation component.Author: Manvendra S. Chauhan, Anil Kumar, Kamla Pathak
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3299447/
Drug release through asymmetric membrane (AM) coating, prepared by phase inversion, is the personification of osmotic drug delivery. Asymmetric membrane prepared by varying types of hydrophobic coating polymers is a network of interconnecting pores.Author: Rahul Dev, Anil Kumar, Kamla Pathak
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