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https://www.sciencedirect.com/science/article/pii/B9781845690700500047
4.1. Introduction. The development of numerous biodegradable polymers for drug delivery applications has been significant but difficulties remain for researchers, who hope to produce efficacious drug release profiles, all while avoiding pharmacological or toxicological effects from the base polymer.Author: G. S. Kwon, D. Y. Furgeson
https://www.sciencedirect.com/science/article/pii/S0927776509004111
Biodegradable polymeric nanoparticles based drug delivery systems. ... Nanoparticles prepared with a blend of a biodegradable polyester PCL and a poly cationic non-biodegradable acrylic polymer have been used as a drug carrier for oral ... Adsorption isotherms for the nanoparticle/drug delivery system is used to give vital information on the ...Author: Avnesh Kumari, Sudesh Kumar Yadav, Subhash Chandra Yadav
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3438887/
POLYMER THERAPEUTICS FOR DRUG DELIVERY. Polymer therapeutics is a term used to describe an increasingly important area of biopaharmaceutics in which a linear or branched polymer chain behaves either as the bioactive (a polymeric drug) or, more commonly, as the inert carrier to which a therapeutic is covalently linked, as in the case of polymer ...Author: William B. Liechty, David R. Kryscio, Brandon V. Slaughter, Nicholas A. Peppas
https://www.researchgate.net/publication/279724491_Biodegradable_Polymers_as_Drug_Delivery_Systems
Biodegradable Polymers as Drug Delivery Systems ... to a new biodegradable polypeptidic polymer for implantable drug delivery system. ... of using PHP ester as a biodegradable gene delivery ...
https://biomedres.us/fulltexts/BJSTR.MS.ID.002056.php
One example of a successful polymeric drug delivery system is Norplant, an implantable contraceptive device. It was oneof the first drug delivery systems to be widely used in clinical practice. However, it is a non-degradable system and therefore requires surgical removal once the drug has depleted.Author: Kiran Dhaliwal, Priya Dosanjh, Jose Sanchez Payá
https://www.mddionline.com/polymers-controlled-drug-delivery
Drug delivery from a typical matrix drug delivery system. For the reservoir systems shown in Figures 3a and 3b, the drug delivery rate can remain fairly constant. In this design, a reservoir whether solid drug, dilute solution, or highly concentrated drug solution within a polymer matrix is surrounded by a film or membrane of a rate-controlling ...
https://patents.google.com/patent/US8128954B2/en
A sustained-release biodegradable polymeric drug-eluting fiber is disclosed. In some embodiments, the therapeutic drug is complexed with cyclodextrin. In certain embodiments, the polymeric component of the fiber comprises cyclodextrin. The fiber may be fabricated to provide a thread and/or suture. The fiber may be used for treatment of ocular diseases or disorders.Author: Mark E. Davis, Kenneth W. Wright, Brendan Mack
https://www.pharmatutor.org/articles/biodegradable-polymers-role-drug-delivery
Examples include Dexon® and Vicryl® sutures prepared from poly (glycolic acid) and poly (lactide-co-glycolide). This led to the development of sustained release drug delivery formulations. In 1970, Yolles et al reported the use of the poly (lactic acid) biodegradable system for …
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