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https://www.technologyreview.com/s/416687/artificial-red-blood-cells-for-drug-delivery/
Dec 15, 2009 · Artificial Red Blood Cells for Drug Delivery. ... Since the 1950s, researchers have been trying to mimic the abilities of red blood cells. These flexible discs carry oxygen throughout the body ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3566225/
The first experimental artificial red blood cells have all three major functions of red blood cells (rbc). However, the first practical one is a simple polyhemoglobin (PolyHb) that only has an oxygen-carrying function. This is now in routine clinical use in South Africa and Russia.Author: Thomas M. S. Chang
https://www.popsci.com/technology/article/2009-12/artificial-blood-cells-aid-drug-delivery-imaging/
Dec 16, 2009 · Artificial Red Blood Cells To Aid Drug Delivery, Imaging . ... For 50 years, scientists have tried to take advantage of that mobility by creating artificial red blood cells.
https://hboc.engineering.osu.edu/research/drug-delivery
Drug Delivery. Targeted delivery of drugs to specific regions or cells in the body is a method used to localize, prolong, and have a protective interaction between a drug and the tissue. In our lab we seek to use hemoglobin as a mediator for active targeted drug delivery to monocytes and macrophages.
https://advances.sciencemag.org/content/5/10/eaaw6870.full
Oct 01, 2019 · Erythrocytes or red blood cells (RBCs) represent a promising cell-mediated drug delivery platform due to their inherent biocompatibility. Here, we developed an antigen delivery system based on the nanoerythrosomes derived from RBCs, inspired by the splenic antigen-presenting cell targeting capacity of senescent RBCs. Tumor antigens were loaded onto the nanoerythrosomes by fusing …Author: Xiao Han, Shufang Shen, Qin Fan, Guojun Chen, Edikan Archibong, Gianpietro Dotti, Zhuang Liu, Zhen G...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2844929/
Introduction: red blood cells as carriers for drug delivery. The optimization of vascular delivery of drugs is an important biomedical problem. This problem is especially acute in case of delivery of potent and specific, yet labile and complex biotherapeutic agents including enzymes, which in most cases require precise localization in the ...
https://www.mcgill.ca/bme/research/artificial-cells-drug-delivery
Artificial Cells & Drug Delivery Artificial cells are small capsules with variations in content, membrane materials, and dimension - from micro to nanoscale. Artificial cells may be used to replace human body cells, for example as a replacement of blood cells and thus alleviate the shortage of blood for transfusion (also see Biomaterials ...
https://www.phlbi.org/divisions/blood-disorders/artificial-blood/
The formed elements are red blood cells (RBCs), white blood cells (WBCs), and platelets. White blood cells are part of the body’s immune system that destroys viruses and bacteria, the pathogens that cause infections. Platelets form clots to prevent bleeding from cuts and small wounds.
https://www.in-pharmatechnologist.com/Article/2009/12/17/Flexible-artificial-blood-cells-could-improve-drug-delivery-says-US-group
Dec 17, 2009 · Artificial red blood cells (RBC) that mimic “biologically optimised” characteristics could better nanotech drug delivery, say US scientists. The team from the University of California modified spherical poly lactic-co-glycolic acid (PLGA) particles using an alcohol treatment until they formed the classic “dimpled” RBC shape.
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