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https://pubs.acs.org/doi/10.1021/nn901374b
Aptamer-Based Tumor-Targeted Drug Delivery for Photodynamic Therapy. ... G-Quadruplex-Based Nanoscale Coordination Polymers to Modulate Tumor Hypoxia and Achieve Nuclear-Targeted Drug Delivery for Enhanced Photodynamic Therapy. Nano Letters 2018, 18 (11) , 6867-6875. DOI: 10.1021/acs.nanolett.8b02732.Author: Yen-An Shieh, Shu-Jyuan Yang, Ming-Feng Wei, Ming-Jium Shieh
https://www.researchgate.net/publication/41485398_Aptamer-Based_Tumor-Targeted_Drug_Delivery_for_Photodynamic_Therapy
For example, Shieh et al. [160] developed an aptamer-based photodynamic therapy strategy by using AS1411 as a drug carrier to target cancer cells ( Figure 3C). Willner and co-workers [186] also ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4033951/
This proof-of-principle study demonstrated that an anti-TN-C aptamer could be used to target tumors (glioma, breast, and colon) that express high level of TN-C and that aptamers, in general, may have pharmacologic properties that make them excellent agents for tumor-specific drug delivery.Author: Partha Ray, Rebekah R. White
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3205327/
Sep 01, 2011 · Tumor-targeted drug delivery is one of the major areas in cancer research. Aptamers exhibit many desirable properties for tumor-targeted drug delivery, such as ease of selection and synthesis, high binding affinity and specificity, low immunogenicity, and versatile synthetic accessibility.Author: Yin Zhang, Hao Hong, Weibo Cai
https://www.sciencedirect.com/science/article/pii/S0142961220302179
1. Introduction. As an effective and noninvasive therapeutic strategy for diseases, primarily cancers, photodynamic therapy (PDT) employs photosensitizers (PS) under light irradiation to produce singlet oxygen (SO) and reactive oxygen species (ROS), to cause DNA damage and cell apoptosis [, , ].However, because the generation of SO exhibits extremely short lifespans (<200 ns) and short ...Author: Yu Yang, Yu Yang, Wenjun Zhu, Liang Cheng, Ren Cai, Xuan Yi, Jiaxuan He, Xiaoshu Pan, Lu Yang, Kai Y...
https://www.researchgate.net/publication/51568610_Tumor-Targeted_Drug_Delivery_with_Aptamers
Cancer is one of the leading causes of death around the world. Tumor-targeted drug delivery is one of the major areas in cancer research. Aptamers exhibit many desirable properties for tumor ...
https://www.sciencedirect.com/science/article/pii/S0169409X1830200X
Phototherapy, such as photodynamic therapy (PDT) and photothermal therapy (PTT), holds great potential for the treatment of a variety of diseases. ... M.-J. ShiehAptamer-based tumor-targeted drug delivery for photodynamic therapy. ACS Nano, 4 (2010), pp. 1433-1442. Google Scholar.Author: Guizhi Zhu, Xiaoyuan Chen
https://freepaper.me/downloads/abstract/10.1021/nn901374b
Aptamer-Based Tumor-Targeted Drug Delivery for Photodynamic Therapy. A specialized G-rich DNA structure, G-quadruplex, has been studied for its special physical characteristics and biological effects. Herein we report a novel strategy of using G-quadruplex as a drug carrier to target cancer cells for photodynamic therapy (PDT).
https://www.nature.com/articles/am201412
Apr 11, 2014 · Based on their unique advantages, increasing interest has been shown in the use of aptamers as target ligands for specific cancer cell recognition and targeted cancer therapy. Recently, the ...Author: Qiaoling Liu, Qiaoling Liu, Chen Jin, Yanyue Wang, Xiaohong Fang, Xiaobing Zhang, Zhuo Chen, Weihong...
https://www.thno.org/v05p0322.htm
122. Shieh Y-A, Yang S-J, Wei M-F, Shieh M-J. Aptamer-based tumor-targeted drug delivery for photodynamic therapy. ACS Nano. 2010;4:1433-42 123. Mallikaratchy P, Tang Z, Tan W. Cell specific aptamer-photosensitizer conjugates as a molecular tool in photodynamic therapy. ChemMedChem. 2008;3:425-8 124.
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