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https://www.tandfonline.com/doi/abs/10.1080/1943085x.2010.488198
Nov 01, 2014 · In this regard, nanotechnology has helped to formulate efficient vaccine delivery systems that can protect the encapsulated antigen from the hostile in vivo environment and can maintain a sustained release that helps to induce the immunostimulatory properties of the vaccine.Author: Abhalaxmi Singh, Ranjita Misra, Chandana Mohanty, Sanjeeb K. Sahoo
https://www.researchgate.net/publication/233142812_Applications_of_Nanotechnology_in_Vaccine_Delivery
Applications of Nanotechnology in Vaccine Delivery. Vaccination is one of the most important medical interventions that helped to eradicate a number of diseases. The crucial parameter in vaccination is to deliver the vaccine in a proper manner to evoke robust immune response.
https://www.sciencedirect.com/science/article/pii/S0169409X08000458
The most common forms of proteosomes used for vaccine applications are nanoparticles composed of the outer membrane proteins (OMPs) of Neisseria meningitidis. OMPs have been used successfully in a marketed meningococcal vaccine since 1981 and are considered non-toxic and well-tolerated,.Author: Laura J. Peek, C. Russell Middaugh, Cory Berkland
https://www.sciencedirect.com/science/article/pii/S181808761400035X
Although the applications of nanotechnologies for nanocarrier-based vaccine delivery are currently in a nascent investigational stage, and only a few products are being tested in clinical trials, these vaccine delivery systems may potentially be used more broadly for the prevention and treatment of …Author: Mi-Gyeong Kim, Joo Yeon Park, Yuna Shon, Gunwoo Kim, Gayong Shim, Yu-Kyoung Oh
https://www.researchgate.net/publication/5525880_Nanotechnology_in_vaccine_delivery
Nanotechnology increasingly plays an important role in vaccine development Nanocarrier-based delivery systems offer an opportunity to increase the cellular and humoral immune responses. The use …
https://link.springer.com/chapter/10.1007/978-3-319-00978-0_19
Sep 16, 2013 · However, the successful immunotherapy depends on several factors such as nature of pathogen, vaccine delivery system, route of administration, and immune system of the host. With the advances in nanotechnology, immunotherapy is now targeting different challenging disorders including cancer as well as infectious diseases.Author: Martin J. D’Souza, Suprita A. Tawde, Archana Akalkotkar, Lipika Chablani, Marissa D’Souza, Maurizio ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4365085/
Jan 23, 2015 · Nanoparticle delivery systems offer the added strength of multi-component loading which is of considerable significance particularly in immunotherapy where simultaneous delivery of antigens, immunoadjuvants, and targeting ligands is ideal [1–8]. Additionally, due to their large surface area, nanoparticles can be readily surface-engineered with proteins, peptides, polymers, cell …Author: Aliasger K. Salem
https://www.sciencedirect.com/science/article/pii/B9780323399814000105
These systems offer the potential to revolutionize the vaccine field by allowing the development of a multipronged approach. In fact, nanotechnology can combine the sustainable delivery of antigens and immune modulators to specific cells with a focus on the development of coordinated and long-lasting immune responses.Author: L. Lambricht, C. Peres, H. Florindo, V. Préat, G. Vandermeulen
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3206135/
4. From engineering to potential applications in medicine. Several vaccines for infectious diseases are based on mammalian VLPs and are already used in the clinic [10,33–35], while similar concepts for the prevention of cancer are also in development .Author: Ibrahim Yildiz, Sourabh Shukla, Nicole F. Steinmetz
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