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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3255397/
Mucoadhesive drug delivery systems have applications from different angles, including development of novel mucoadhesives, design of the device, mechanisms of mucoadhesion and permeation enhancement. With the influx of a large number of new drug molecules due to drug discovery, mucoadhesive drug delivery will play an even more important role in ...
https://www.sciencedirect.com/science/article/pii/S1381514816300104
Scientists have reviewed applications of mucoadhesive polymers in drug delivery. Brooks reviewed the potentials of natural mucoadhesive biopolymers, silk and silk-like proteins, in controlled drug delivery and suggested that these biocompatible polymeric matrixes could have promising potential particularly in local controlled drug delivery including their role in the mitigation of immune ...Author: Shakir Mansuri, Prashant Kesharwani, Prashant Kesharwani, Keerti Jain, Rakesh K. Tekade, N.K. Jain
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3053525/
Gastrointestinal Mucoadhesive Drug Delivery Systems. Oral route is undoubtedly most favored route of administration, but hepatic first-pass metabolism, degradation of drug during absorption, mucus covering GI epithilia, and high turnover of mucus are serious concerns of oral route.
https://www.researchgate.net/publication/326003441_Applications_of_natural_polymers_in_mucoadhesive_drug_delivery_An_overview
Aim of this review is to compile the current literature with special focus on role of natural polymers on mucoadhesive drug delivery system. Mucodhesion refers to bond formed between two ...
https://www.researchgate.net/publication/221750117_Mucoadhesive_drug_delivery_system_An_overview
Mucoadhesive drug delivery systems interact with the mucus layer covering the mucosal epithelial surface, and mucin molecules and increase the residence time of the dosage form at the site of ...
https://www.tandfonline.com/doi/abs/10.1081/DDC-100101318
Apr 02, 2012 · They are also finding numerous applications in oral mucoadhesive drug delivery because of their ability to interact with the mucus glycoprotein and to remain localized to a specific site. The present review aims at giving an insight into the potential application of …Author: Anil K. Singla, Manish Chawla, Amarjit Singh
https://en.wikipedia.org/wiki/Mucoadhesion
The consolidation stage of mucoadhesion involves the establishment of adhesive interactions to reinforce strong or prolonged adhesion. When moisture is present, mucoadhesive materials become activated and the system becomes plasticized. This stimulus allows the mucoadhesive molecules to separate and break free while proceeding to link up by weak van der Waals and hydrogen bonds.
https://www.sciencedirect.com/science/article/pii/B9780128097175000129
The main components of bioadhesive drug delivery systems are bioadhesive polymers, which may be natural or synthetic in nature. The success of bioadhesive drug delivery systems depends upon bioadhesion bonding, which is influenced by polymer-based properties like chain length, cross linking, and presence of various functional groups.Author: Lalit Kumar, Shivani Verma, Bhuvaneshwar Vaidya, Vivek Gupta
https://www.pharmatutor.org/articles/oral-mucoadhesive-drug-delivery-systems-review
About Authors: Saumya Samanta1, Ranabir Chanda2, Jyotishman Bhattacharya3 Benagal School of Technology, Chuchura, West Bengal, India *[email protected] ABSTRACT Formulations of mucoadhesive polymers are of current interest in the design of drug delivery systems. Current uses of mucoadhesive based preparations include ophthalmic solutions, local applications to treat
https://journal.pda.org/content/66/5/466
Sep 01, 2012 · LAY ABSTRACT: Over the past few decades the mucoadhesive buccal drug delivery system has received a great deal of attention to develop mucoadhesive dosage forms to enable the prolonged retention at the site of action, providing a controlled release of …Author: Dattatraya Manohar Shinkar, Avinash Sridhar Dhake, Chitral Mallikarjuna Setty
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