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https://www.researchgate.net/profile/Sunil_Kumar_Battu/publication/23553368_Application_of_hot-melt_extrusion_for_drug_delivery/links/0fcfd5014996fda843000000.pdf
Applications of hot-melt extrusion for drug delivery 1358 Expert Opin. Drug Deliv. (2008) 5(12) miscibility of guaifenesin and ketoprofen in polyethylene oxide (PEO) was predicted by calculating ...
https://www.researchgate.net/publication/23553368_Application_of_hot-melt_extrusion_for_drug_delivery
However, over the last decade hot-melt extrusion (HME) has emerged as a powerful processing technology for drug delivery and has opened the door to a host of molecules previously considered unviable as drugs. HME is considered to be an efficient technique in …
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6321644/
Oct 24, 2018 · During the hot-melt extrusion process of pharmaceutical dosage forms, APIs, thermoplastic polymeric carrier and processing aids such as plasticisers and antioxidants, are heated and mixed in the extruder and then being forced through a die into shapes including granules, cylinder or films .Author: Deck Khong Tan, Mohammed Maniruzzaman, Ali Nokhodchi
https://europepmc.org/articles/PMC5821067
Dec 01, 2008 · In recent years, an insight into hot-melt extrusion techniques has revealed another novel application of targeted drug delivery to the colon . The feasibility of hot-melt extruded tablets of 5-ASA in an Eudragit ® S100 polymeric matrix for colon targeting was demonstrated by Bruce et al. Citric acid was utilized as a solid state plasticizer and TEC was used as a liquid plasticizer in this study.Author: Michael A Repka, Soumyajit Majumdar, Sunil Kumar Battu, Ramesh Srirangam, Sampada B Upadhye
https://www.academia.edu/14742263/Applications_of_hot-melt_extrusion_for_drug_delivery
Hot-melt extrusion in drug delivery In today’s pharmaceutical arena, it is estimated that more than 40% of new 3. Conclusions and scope chemical entities produced during drug discovery efforts exhibit poor solubility characteristics. However, over the last decade hot-melt extrusion 4.
https://www.wiley.com/en-us/Hot+Melt+Extrusion%3A+Pharmaceutical+Applications-p-9781118307878
Apr 24, 2012 · Hot-Melt Extrusion: Pharmaceutical Applications is an essential multidisciplinary guide to the emerging pharmaceutical uses of this processing technology for researchers in academia and industry working in drug formulation and delivery, pharmaceutical engineering and processing, and polymers and materials science.Author: Dennis Douroumis
https://onlinelibrary.wiley.com/doi/book/10.1002/9780470711415
Apr 26, 2012 · Hot-Melt Extrusion: Pharmaceutical Applications is an essential multidisciplinary guide to the emerging pharmaceutical uses of this processing technology for researchers in academia and industry working in drug formulation and delivery, pharmaceutical engineering and processing, and polymers and materials science.
https://cdn.intechopen.com/pdfs/40644/InTech-Hot_melt_extrusion_hme_from_process_to_pharmaceutical_applications.pdf
In this chapter we review the hot-melt extrusion technique, based on a holistic perspective of its various components, processing technologies as well as the materials and novel formulation design and developments to its varied applications in oral drug delivery systems. 2. Hot-melt extrusion (HME): Process technology
https://www.sciencedirect.com/science/article/pii/S0939641102000619
The most important application of extrusion in the pharmaceutical industry is in the preparation of granules or pellets of uniform size, ... Application of melt extrusion as drug delivery technology. ... Influence of plasticizers and drugs on the physical–mechanical properties of hydroxypropylcellulose films prepared by hot-melt extrusion.Author: Jörg Breitenbach
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