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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3131585/
4. Gene Delivery Using MNPs and Magnetic Force. The mechanism of magnetofection is similar to using transfection reagents (Lipofectamine 2000, FuGENE HD, and PEI). The only difference is that the plasmids form complexes with cationic polymer-coated MNPs (called as …Author: Daisuke Kami, Shogo Takeda, Yoko Itakura, Satoshi Gojo, Masatoshi Watanabe, Masashi Toyoda
https://www.mdpi.com/1422-0067/12/6/3705/htm
Nanoparticles are already being used clinically to enhance MRI imaging, and drug delivery for cancer patients. Our own research has focused on gene delivery systems for autologous cell transplantation therapy, in which the patient’s own cells are transfected with the gene required to correct their condition.Author: Daisuke Kami, Shogo Takeda, Yoko Itakura, Satoshi Gojo, Masatoshi Watanabe, Masashi Toyoda
https://www.mdpi.com/1422-0067/12/6/3705/pdf
Application of Magnetic Nanoparticles to Gene Delivery Daisuke Kami 1,*, Shogo Takeda 2, Yoko Itakura 1, Satoshi Gojo 1, Masatoshi Watanabe 2 and Masashi Toyoda 1 1 Research Team for Vascular Medicine, Tokyo Metropolitan Institute of Gerontology, ... nanoparticles. , , gene delivery. , , , , , ...Author: Daisuke Kami, Shogo Takeda, Yoko Itakura, Satoshi Gojo, Masatoshi Watanabe, Masashi Toyoda
https://www.researchgate.net/publication/51484309_Application_of_Magnetic_Nanoparticles_to_Gene_Delivery
Therefore, the synergistic action of Poly-MAG and exogenous magnetic field could not only mediate the gene delivery of “Yamanaka factor”, but also enhance the transmembrane of functional ...
https://www.tandfonline.com/doi/pdf/10.3109/21691401.2015.1014093
For gene delivery, magnetic nanoparticles (MNPs) are typically combined with a delivery platform to encapsulate the gene, and promote cell uptake.
https://pubs.rsc.org/en/content/articlelanding/2020/tb/d0tb00217h
Due to the presence of cell wall, delivery of biomolecules such as nucleic acids is a major challenge, which limits the applications of nanomaterials in genetic engineering-mediated crop improvement. However, in recent years, use of various nanomaterials like carbon nanotubes, magnetic nanoparticles, mesoporous silica nanoparticles, etc. for ...
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