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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3066533/
Mar 01, 2011 · Among them liposomal formulations were widely explored in the last decade for drug delivery applications. In 1965 liposomes were first introduced as the drug delivery carriers . Liposomes are usually within the size range of 10 nm to 1 μm or greater. These vesicular systems are composed of aqueous core enclosed by phospholipid bilayers of natural or synthetic origin.Author: Gyan P. Mishra, Mahuya Bagui, Viral Tamboli, Ashim K. Mitra
https://www.omicsonline.org/open-access/liposomes-for-drug-delivery-2155-952X276-97370.html
Some of the major therapeutic applications of liposomes in drug delivery include: Site-avoidance delivery The cytotoxicity of anti-cancer drugs to normal tissues is attributed to their narrow therapeutic index (TI).Author: Durgavati Yadav, Kumar Sandeep, Deepak Pandey, Ranu Kumari Dutta
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4664963/
Dec 01, 2015 · The application of liposomes to assist drug delivery has already had a major impact on many biomedical areas. They have been shown to be beneficial for stabilizing therapeutic compounds, overcoming obstacles to cellular and tissue uptake, and improving biodistribution of compounds to …Author: Lisa Sercombe, Tejaswi Veerati, Tejaswi Veerati, Fatemeh Moheimani, Sherry Y. Wu, Anil K. Sood, Susa...
https://www.nature.com/articles/s41598-017-11533-1
Sep 21, 2017 · Liposomes are a well-established formulation strategy to improve drug delivery and enhance therapeutic outcomes for a range of drugs, such as …Author: Nikolay Dimov, Elisabeth Kastner, Maryam Tabassum Hussain, Yvonne Perrie, Nicolas Szita
https://www.sciencedirect.com/topics/pharmacology-toxicology-and-pharmaceutical-science/liposomal-drug-delivery
In the past two decades there have been major advances in the development of liposomal drug delivery systems suitable for applications ranging from cancer chemotherapy to gene therapy. In general, an optimized system consists of liposomes with a diameter of ∼100 nm that possess a long circulation lifetime (half-life >5 h).
https://deepblue.lib.umich.edu/bitstream/handle/2027.42/28412/0000187.pdf?sequence=1
Mezei and Gulasekharam [11] reported that topical application. of liposomal triamcinolone acetonide for 5 days resulted in a drug concentration in. the epidermis and dermis four times higher than that obtained using a control oint-. ment, while urinary excretion of the drug was diminished.
https://www.sciencedirect.com/science/article/pii/S0169409X12002980
Liposomal drug delivery systems: From concept to clinical applications ☆ 1. Introduction: the pioneers. 2. Designing liposomes to achieve optimized properties. 3. Receptor-mediated endocytosis of ligand-targeted liposomes. 4. Triggered release. 5. Delivery of nucleic acids and DNA. 6. ...Author: Theresa M. Allen, Pieter R. Cullis
https://www.azonano.com/article.aspx?ArticleID=4668
Nov 01, 2017 · Nanotechnology drug delivery applications occur through the use of designed nanomaterials as well as forming delivery systems from nanoscale molecules such as liposomes. Applying nanotechnology to drug delivery should achieve the following benefits: Improve the ability to deliver drugs that are poorly water soluble.Author: Azonano
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