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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2527668/
The kind of hazards that are introduced by using nanoparticles for drug delivery are beyond that posed by conventional hazards imposed by chemicals in classical delivery matrices. For nanoparticles the knowledge on particle toxicity as obtained in inhalation toxicity shows the way how to investigate the potential hazards of nanoparticles.Author: Wim H De Jong, Paul Ja Borm
https://www.sciencedirect.com/science/article/pii/S0531513105000853
The nanoparticles may be endocytosed by the endothelial cells followed by the release of the drugs within these cells and delivery to the brain. 5. The nanoparticles with bound drugs could be transcytosed through the endothelial cell layer. 6. The polysorbate 80 used as the coating agent could inhibit the efflux system, especially P ...Author: Jörg Kreuter
https://www.researchgate.net/publication/223422597_Application_of_nanoparticles_for_the_delivery_of_drugs_to_the_brain
One of the possibilities to overcome this barrier is drug delivery to the brain using nanoparticles. Drugs that have been transported into the brain and led to significant pharmacological effects ...Author: Jörg Kreuter
https://www.sciencedirect.com/science/article/abs/pii/S0531513105000853
One of the possibilities to overcome this barrier is drug delivery to the brain using nanoparticles. Drugs that have been transported into the brain and led to significant pharmacological effects after intravenous injection using this carrier include the hexapeptide dalargin, the dipeptide kytorphin, loperamide, tubocurarine, doxorubicin, and ...Author: Jörg Kreuter
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6306759/
Nov 27, 2018 · The use of nanoparticles to diagnose brain diseases or to assist the delivery of drugs across the blood brain barrier has gained a great interest, since they offer a series of advantages, namely targeting efficiency, non-invasiveness, biodegradability, stability, and controllability to …Author: Daniel Mihai Teleanu, Cristina Chircov, Alexandru Mihai Grumezescu, Adrian Volceanov, Raluca Ioana T...
https://en.wikipedia.org/wiki/Nanoparticles_for_drug_delivery_to_the_brain
Nanoparticles for drug delivery to the brain is a method for transporting drug molecules across the blood–brain barrier (BBB) using nanoparticles.These drugs cross the BBB and deliver pharmaceuticals to the brain for therapeutic treatment of neurological disorders.
https://phys.org/news/2014-12-gelatin-nanoparticles-drugs-brain.html
Dec 24, 2014 · The researchers found that gelatin nanoparticles could be laced with medications for delivery to the brain, and that they could extend the treatment window for …
https://www.researchgate.net/publication/233745208_Nanoparticles_for_brain_delivery_of_drugs_or_contrast_agents_Application_to_Alzheimer's_disease
[Nanoparticles for brain delivery of drugs or contrast agents. Application to Alzheimer's disease.] Article · Literature Review in Biologie Aujourd'hui 206(3):185-190 · November 2012 with 24 Reads
https://www.future-science.com/doi/pdfplus/10.4155/tde.15.56
targeted delivery of magnetic nanoparticles to the brain with the application of an external magnetic field. The BBB & the neurovascular unit Neurons are fragile cells with a high dependency on the homeostatic mechanisms that regulate their micro - environment. Nonfenestrated brain endothelial cells and their intermingling tight junctions ...
https://www.hindawi.com/journals/isrn/2013/238428/
As a consequence, several strategies are currently being sought after to enhance the delivery of drugs across the BBB. Within this review, the recently born strategy of brain drug delivery based on the use of nanoparticles, multifunctional drug delivery systems with size in …Author: Massimo Masserini
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