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https://www.ncbi.nlm.nih.gov/pubmed/29756237
Biopolymers for Antitumor Implantable Drug Delivery Systems: Recent Advances and Future Outlook. ... Novel emerging biopolymers as well as cutting-edge polymeric microdevices deployed as implantable antitumor DDSs are discussed. Finally, a review of a new therapeutic modality within the field, which is based on implantable biopolymeric DDSs, is ...Author: Sepehr Talebian, Sepehr Talebian, Javad Foroughi, Javad Foroughi, Samantha J. Wade, Samantha J. Wade...
https://www.sciencedirect.com/science/article/pii/S0141813016303452
The resulting ASN were investigated for the capability to load and release doxorubicin hydrochloride (DOX), and the antitumor activities of DOX-loaded SN and DOX-loaded ASN were evaluated as potential drug delivery systems for cancer therapy.Author: Huaxi Xiao, Tao Yang, Qinlu Lin, Gao-Qiang Liu, Lin Zhang, Fengxiang Yu, Yuejiao Chen
https://www.sciencedirect.com/science/article/pii/S2211383518307202
Red blood cell membrane-camouflaged nanoparticles: a novel drug delivery system for antitumor application. ... Over previous decades, nanoparticle-based drug delivery systems (DDS) have been successfully applied experimentally and clinically to improve the …Author: Qing Xia, Yongtai Zhang, Zhe Li, Xuefeng Hou, Nianping Feng
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5634382/
Oct 05, 2017 · For this purpose, various antitumor drug-loaded nanocarriers were used for their chemotherapeutic action as novel techniques for the targeted drug delivery through the locoregional lymphatics, leading to improved drug delivery and targeting tumorous cells with the lowest systemic toxicity while retaining therapeutic systemic levels.117Author: Fakhar ud Din, Waqar Aman, Izhar Ullah, Omer Salman Qureshi, Omer Mustapha, Shumaila Shafique, Alam ...
https://pubs.acs.org/doi/10.1021/acs.chemmater.7b00047
Programmed drug delivery was achieved by a dual response of the extracellular acid and intracellular reductive environment. In vitro studies of the SDDS made it possible to visualize faster cellular uptake at pH 6.8 than at pH 7.4 because of the re-exposure of cationic charges and subsequent successful delivery of CPT to the cell nucleus.Author: Wenyu Cheng, Hong Cheng, Shuangshuang Wan, Xianzheng Zhang, Meizhen Yin
https://pubs.acs.org/doi/10.1021/acs.molpharmaceut.0c00014
Currently, clinically-used anti-tumor nanomedicine is usually insufficient to eradicate malignancies, due to the tumor stroma exerting therapeutic resistance and physical barriers for a proper drug delivery. As the most abundant cells in tumor stroma, cancer-associated fibroblasts (CAFs) produce a critical tumor-promoting effect and barriers preventing the physical delivery of nanomedicines ...Author: Jian Guo, Huating Zeng, Yan Chen
https://www.hindawi.com/journals/jnm/2020/7147130/
A dual-targeting drug delivery system (DTDDS) with magnetic targeting and active targeting was obtained to improve the targeting and drug-loading capacity of magnetic drug nanocarriers. An ultraviolet-visible spectrophotometer and flow cytometry were used to investigate the drug-loading and release capacity, cytotoxicity, and inhibition of tumor cell proliferation, separately. Results show ...Author: Jinglei Du, Qiang Li, Lin Chen, Shicai Wang, Li Zhang, Shiping Yu, Shiping Yu, Yongzhen Yang, Xuguan...
https://onlinelibrary.wiley.com/doi/abs/10.1002/adma.201900795
Abstract Biomimetic camouflage, i.e., using natural cell membranes for drug delivery, ... In mouse cancer models, it shows significantly better antitumor efficacy than nanoformulations based on a platesome without pH responsiveness or those based on traditional pH‐sensitive liposomes. A convenient way to incorporate stimuli‐responsive ...Author: Guangna Liu, Guangna Liu, Guangna Liu, Xiao Zhao, Yinlong Zhang, Yinlong Zhang, Junchao Xu, Junchao ...
https://www.nature.com/articles/srep34053
Oct 11, 2016 · Combinatorial nanocarrier based drug delivery approach for amalgamation of anti-tumor agents in breast cancer cells: an improved nanomedicine strategy ... The enhanced antitumor …Author: Chandran Murugan, Kathirvel Rayappan, Ramar Thangam, Ramasamy Bhanumathi, Krishnamurthy Shanthi, Raj...
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