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https://www.nature.com/articles/1395869
Nov 28, 2001 · The purpose of this study is to determine the feasibility of creating surgically implantable delivery systems for antipsychotic medication to help patients …Author: Steven J Siegel, Karen I Winey, Raquel E Gur, Robert H Lenox, Warren B Bilker, Debbie Ikeda, Neel Ga...
https://www.researchgate.net/publication/232918770_Delivery_Systems_and_Dosing_for_Antipsychotics
Delivery Systems and Dosing for Antipsychotics 285 With an understanding of the benefits and limitations of depots, we introduced the idea of using implantable systems for long-term medication ...
https://libiresearch.research.chop.edu/sites/default/files/files/Surgically%20implantable%20long-term%20antipsychotic%20delivery%20systems%20for%20the%20treatment%20of%20schizophrenia.pdf
delivery systems for antipsychotic medication to help patients with schizophrenia with long-term adherence. METHODS Implant Fabrication Implants were fabricated through solvent casting and compression-molding. Two polymers, 75% polylactide with 25% polyglycolide (75:25 PLGA) and 85% polylac-tide with 15% polyglycolide (85:15 PLGA) are presented
https://www.ncbi.nlm.nih.gov/pubmed/10852342
Although some new antipsychotic agents have been marketed to offer broader efficacy with much reduced side-effect profiles, the drug delivery systems for antipsychotics are still in the stage of conventional dosage forms, such as tablets, capsules and solutions, and need to be dosed at the frequency of 2-4 times daily.Author: Yu-Hui Cheng, L. Illum, S. Davis
https://repository.upenn.edu/cgi/viewcontent.cgi?article=1136&context=mse_papers
antipsychotic delivery system in rodents and rabbits Abstract Rationale: Non-adherence with medication remains the major correctable cause of poor outcome in schizophrenia. However, few treatments have addressed this major determinant of outcome with novel long-term delivery systems.Author: Kayla L. Metzger, Jody M. Shoemaker, Jonathan B. Kahn, Christina R. Maxwell, Yuling Liang, Jan Tokar...
https://www.researchgate.net/publication/11363105_Surgically_Implantable_Long-term_Antipsychotic_Delivery_Systems_for_the_Treatment_of_Schizophrenia
Surgically Implantable Long-term Antipsychotic Delivery Systems for the Treatment of Schizophrenia Article in Neuropsychopharmacology 26(6):817-23 · July 2002 with 187 Reads How we measure 'reads'
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3000189/
Objective: An overview of the emerging field of long-term delivery strategies for improved convenience and adherence with psychiatric medications is provided. This review is motivated by the hypothesis that adherence to treatment is an important determinant of clinical outcomes in a wide range of settings and is particularly important in psychiatry practice where patients require treatment for ...
https://www.psychiatrictimes.com/schizophrenia/schizophrenia-treatment-challenges
Siegel SJ, Winey KI, Gur RE et al. (2002), Surgically implantable long-term antipsychotic delivery systems for the treatment of schizophrenia. Neuropsychopharmacology 26(6):817-823. 13. Valenstein M, Copeland LA, Blow FC et al. (2002), Pharmacy data identify poorly adherent patients with schizophrenia at increased risk for admission.Author: Donna A. Wirshing, Peter F. Buckley
https://www.tandfonline.com/doi/abs/10.3109/10611860008996856
Oct 20, 2008 · Although some new antipsychotic agents have been marketed to offer broader efficacy with much reduced side-effect profiles, the drug delivery systems for antipsychotics are still in the stage of conventional dosage forms, such as tablets, capsules and solutions, and need to be dosed at the frequency of 2-4 times daily.Author: Yu-Hui Cheng, L. Illum, S. Davis
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