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https://www.medlink.com/article/drug_delivery_to_the_central_nervous_system
Overview. The delivery of drugs to the brain is a challenge in the treatment of CNS disorders. The major obstruction to CNS drug delivery is the blood-brain barrier, which limits the access of drugs to the brain substance.This article describes various strategies to facilitate drug …
https://www.researchgate.net/publication/226613155_An_Overview_of_Drug_Delivery_to_the_CNS
Request PDF An Overview of Drug Delivery to the CNS Limitation of drug delivery to the central nervous system (CNS) is a major problem in development of successful treatment of CNS disorders ...Author: Kewal Jain
https://www.hindawi.com/journals/bmri/2014/869269/
Present review highlights various drug delivery systems used for delivery of pharmaceutical agents mainly antibiotics, antineoplastic agents, neuropeptides, and other therapeutic substances through the endothelial capillaries (BBB) for CNS therapeutics. In addition, the use of ultrasound in delivery of therapeutic agents/biomolecules such as proline rich peptides, prodrugs ...Author: Ravi Kant Upadhyay
https://www.nature.com/articles/nrd.2015.21
Jan 22, 2016 · Research on the blood–brain barrier (BBB) has led to the concept of a complex, dynamic interface between the central nervous system (CNS) and periphery. Banks considers how this new ...Author: William A. Banks
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6409749/
Feb 17, 2019 · 3. General Overview of NEs for Nose-to-Brain Delivery. The easiest classification of NEs designed for nose-to-brain delivery is based on the drug loaded and the therapeutic purpose. As the final target is the brain through the nose, the pharmacological actions regard pathologies of the CNS.Author: Maria Cristina Bonferoni, Silvia Rossi, Giuseppina Sandri, Franca Ferrari, Elisabetta Gavini, Giovan...
https://link.springer.com/protocol/10.1007%2F978-1-60761-529-3_1
Nov 25, 2009 · Limitation of drug delivery to the central nervous system (CNS) is a major problem in development of successful treatment of CNS disorders. Concepts of blood–brain barrier (BBB), its role in transport of various substances from the blood to the brain, as well as strategies to deliver drugs across the BBB have evolved over the past century.Author: Kewal K. Jain
https://www.prnewswire.com/news-releases/global-cns-drug-delivery-market-insights--outlook-2017-2028---cell--gene-therapies-will-play-an-important-role-in-the-treatment-of-neurological-disorders-in-the-future-301022410.html
Global CNS Drug Delivery Market Insights & Outlook, 2017-2028 - Cell & Gene Therapies Will Play an Important Role in the Treatment of Neurological Disorders in the Future
https://www.sciencedirect.com/topics/neuroscience/central-nervous-system
Brian G. Ballios, ... Molly S. Shoichet, in Principles of Regenerative Medicine (Second Edition), 2011. Introduction. The human central nervous system (CNS) is a network of more than 100 billion individual nerve cells that control our actions, sense our surroundings, and define who we are. The CNS is comprised of the brain, spinal cord, and retina. The functional units of the CNS are neurons ...
https://www.sciencedirect.com/book/9780128139974/nervous-system-drug-delivery
These mechanisms often affect the efficiency and specificity of CNS drug delivery. This chapter presents an overview of barriers to CNS drug delivery and identifies mechanisms to overcome the protective defenses of the CNS, allowing targeted therapy for specific disease entities.
https://www.researchgate.net/publication/23796829_CNS_Drug_Delivery_Systems_Novel_Approaches
CNS Drug Delivery Systems: Novel Approaches. ... patients suffering from fatal and/or debilitating central nervous system (CNS) diseases, such as brain tumours, HIV encephalopathy, epilepsy ...
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