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https://www.sciencedirect.com/science/article/pii/S1097276502007104
Despite the critical need for iron in many cellular reactions, deletion of the transferrin pathway does not block organogenesis, suggesting the presence of alternative methods to deliver iron. We show that a member of the lipocalin superfamily (24p3/Ngal) delivers iron to the cytoplasm where it activates or represses iron-responsive genes.Author: Jun Yang, David Goetz, Jau-Yi Li, Wenge Wang, Kiyoshi Mori, Daria Setlik, Tonggong Du, Hediye Erdjum...
https://www.cell.com/molecular-cell/fulltext/S1097-2765(02)00710-4?large_figure=true
Nov 01, 2002 · An Iron Delivery Pathway Mediated by a Lipocalin Previous Article The Neutrophil Lipocalin NGAL Is a Bacteriostatic Agent that Interferes with Siderophore-Mediated Iron Acquisition Next Article Amplification of B Cell Antigen Receptor Signaling by a Syk/ITAM Positive Feedback LoopAuthor: Jun Yang, David Goetz, Jau-Yi Li, Wenge Wang, Kiyoshi Mori, Daria Setlik, Tonggong Du, Hediye Erdjum...
https://www.ncbi.nlm.nih.gov/pubmed/12453413
An iron delivery pathway mediated by a lipocalin. Yang J(1), Goetz D, Li JY, Wang W, Mori K, Setlik D, Du T, Erdjument-Bromage H, Tempst P, Strong R, Barasch J. Author information: (1)College of Physicians and Surgeons of Columbia University, New York, NY 10032, USA.Author: Jun Yang, David Goetz, Jau-Yi Li, Wenge Wang, Kiyoshi Mori, Daria Setlik, Tonggong Du, Hediye Erdjum...
https://www.sciencedirect.com/science/article/abs/pii/S1097276502007104
An Iron Delivery Pathway Mediated by a Lipocalin. ... suggesting the presence of alternative methods to deliver iron. We show that a member of the lipocalin superfamily (24p3/Ngal) delivers iron to the cytoplasm where it activates or represses iron-responsive genes. Iron unloading depends on the cycling of 24p3/Ngal through acidic endosomes ...Author: Jun Yang, David Goetz, Jau-Yi Li, Wenge Wang, Kiyoshi Mori, Daria Setlik, Tonggong Du, Hediye Erdjum...
https://www.researchgate.net/publication/11016967_An_Iron_Delivery_Pathway_Mediated_by_a_Lipocalin
In fact, in recent years, lipocalin-2 (LCN2) has emerged as an alternative pathway for physiological iron delivery and uptake ( Yang et al. 2002). Known for its role in immune responses to limit ...
https://www.cell.com/molecular-cell/pdf/S1097-2765(02)00710-4.pdf
ever, specific iron delivery pathways are unknown. Introduction The cardinal feature of kidney development is the for-mation of epithelial tubules from nonepithelial mesen-The delivery of iron to cells is critical for cell growth and chymal cells. The conversion of cell type is controlled development.
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