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https://www.sciencedirect.com/science/article/pii/S0924424797803056
Shape memory alloy actuators feature an extremely high power-to-volume ratio. This property is a major advantage for miniature applications. This paper describes implantable drug-delivery systems based on shape memory alloy micro-actuation. A first type is designed for use with solid drugs while a second design enables delivery of liquid drugs.Author: Dominiek Reynaerts, Jan Peirs, Hendrik Van Brussel
https://www.deepdyve.com/lp/elsevier/an-implantable-drug-delivery-system-based-on-shape-memory-alloy-micro-yu3JX57fzG
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https://link.springer.com/chapter/10.1007%2F978-3-642-59768-8_23
In a first paragraph, solid drug delivery systems will be discussed. Main part of the chapter will concentrate on the design of a liquid drug delivery system. The proposed design is particular because the shape memory actuated microvalve has only silicone parts in direct contact with the drug.Author: Dominiek Reynaerts, Jan Peirs, Hendrik Van Brussel
https://www.sciencedirect.com/science/article/pii/S0924424799001910
This paper describes the design of a prototype gastro-intestinal intervention system based on an inchworm-type of mobile robot. This type of device is a kind of vehicle for inspection through the colon, something that is currently impossible due to the large number of turns in the intestinal system.Author: Dominiek Reynaerts, Jan Peirs, Hendrik Van Brussel
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3348997/
With the adjustability in flow rate offered by our system, a multitude of pharmacodynamic responses can be studied in a way that has not been possible until now. We also demonstrate, for the first time, an implantable MEMS micropump system for controlled dose, timing, and location of drug delivery in mice.Author: Heidi Gensler, Roya Sheybani, Po-Ying Li, Ronalee Lo Mann, Ellis Meng
http://iopscience.iop.org/article/10.1088/0960-1317/21/7/075005/pdf
PDMS-based dual-channel pneumatic micro-actuator ... Each shape-memory-alloy actuator is driven by a wireless resonant heater which ... For implantable drug-delivery devices, for example, this ability may be utilized to enable a controlled and selective delivery of different types
https://www.researchgate.net/profile/Jan_Peirs
An implantable drug-delivery system based on shape memory alloy micro-actuation. ... Design of a shape memory alloy actuated implantable drug delivery system. ... A Position Sensor for a Micro ...
https://iopscience.iop.org/article/10.1088/0960-1317/21/7/075005/meta
Jun 03, 2011 · Yaguchi H and Tsurumoto K 2005 Wireless-type magnetic micro-actuator capable of movement in a ... Peirs J and Van Brussel H 1997 An implantable drug-delivery system based on shape memory alloy micro ... Sandström N and Stemme G 2009 Wafer-scale manufacturing of bulk shape-memory-alloy microactuators based on adhesive bonding of titanium ...Author: Mohamed Sultan Mohamed Ali, Mohamed Sultan Mohamed Ali, K. Takahata
https://www.researchgate.net/publication/224308325_New_Implantable_Hearing_Device_Based_on_a_Micro-Actuator_that_is_Directly_Coupled_to_the_Inner_Ear_Fluid
The key component of this therapy based on an implantable hearing device is a micro-actuator that is implanted in the mastoid right behind the external auditory canal of a patient.
https://link.springer.com/referenceworkentry/10.1007%2F978-0-387-48998-8_1580
Reynaerts D, Peirs J, Brussel H (1997) An implantable drug-delivery system based on shape memory alloy micro-actuation. Sens Actuators A 61:455–462 Google Scholar 19.
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