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https://onlinelibrary.wiley.com/doi/full/10.1002/jps.10397
Amphiphilic block copolymers (ABCs) have been used extensively in pharmaceutical applications ranging from sustained‐release technologies to gene delivery. The utility of ABCs for delivery of therapeutic agents results from their unique chemical composition, which is characterized by a hydrophilic block that is chemically tethered to a hydrophobic block.Author: Monica L. Adams, Afsaneh Lavasanifar, Glen S. Kwon
https://www.tandfonline.com/doi/abs/10.1080/17425247.2018.1529756
Sep 25, 2018 · Introduction : Nanostructured delivery vehicles can address key challenges facing drug delivery, including the lipophilic nature of therapeutic compounds and their effective transport through the body. Amphiphilic block copolymers that self-assemble offer advantages compared with homopolymer-, lipid-, and protein-based delivery vehicles.Author: Andrew M. Bodratti, Paschalis Alexandridis
https://www.sciencedirect.com/science/article/pii/S0022354916312849
Amphiphilic block copolymers (ABCs) have been used extensively in pharmaceutical applications ranging from sustained-release technologies to gene delivery. The utility of ABCs for delivery of therapeutic agents results from their unique chemical composition, which is characterized by a hydrophilic block that is chemically tethered to a hydrophobic block.Author: Monica L. Adams, Afsaneh Lavasanifar, Glen S. Kwon
https://www.sciencedirect.com/science/article/abs/pii/S0022354916312849
Amphiphilic block copolymers (ABCs) have been used extensively in pharmaceutical applications ranging from sustained-release technologies to gene delivery.Author: Monica L. Adams, Afsaneh Lavasanifar, Glen S. Kwon
https://www.researchgate.net/publication/10696714_Amphiphilic_block_copolymers_for_drug_delivery
Amphiphilic block copolymers (ABCPs), having hydrophilic and hydrophobic chains, have been used to deliver drug in the form of nanoparticles or micelles as they are readily dispersible in water....
https://www.frontiersin.org/articles/10.3389/fmats.2015.00064/full
Oct 14, 2015 · Drug delivery in amphiphilic copolymers. A combination of MD simulation and docking calculation was employed to predict the compatibility between three hydrophobic model drugs (curcumin, paclitaxel, and vitamin D3) and a triblock copolymer poly(ethylene oxide)-desaminotyrosyl-tyrosine octyl esters-poly(ethylene oxide) (PEG–DTO–PEG).Author: Naresh Thota, Jianwen Jiang
https://www.sciencedirect.com/science/article/pii/S0169409X01002228
A final feature that makes amphiphilic block copolymers attractive for drug delivery applications is the fact that their chemical composition, total molecular weight, and block length ratios can be easily changed, which allows control of the size and morphology of the micelles [4], [5].Author: Annette Rösler, Guido W.M Vandermeulen, Harm-Anton Klok
https://www.sciencedirect.com/science/article/pii/B9780128179093000054
Nanoassemblies from amphiphilic block copolymers are a promising approach as nanomedicine platforms for cancer diagnosis and therapy due to their relatively small size, high drug loading capacity, controlled drug release, in vivo stability and prolonged blood circulation.Author: Nidhi Raval, Dnyaneshwar Kalyane, Rahul Maheshwari, Rakesh K. Tekade
https://pubs.acs.org/doi/abs/10.1021/acs.bioconjchem.7b00330
The amphiphilic block copolymer anticancer drug nanocarriers clinically used or in the progress of clinical trials frequently suffer from modest final therapeutic efficacy due …Author: Wendong Ke, Zengshi Zha, Jean Felix Mukerabigwi, Weijian Chen, Yuheng Wang, Chuanxin He, Zhishen Ge
https://www.sciencedirect.com/science/article/pii/S1773224717301077
An amphiphilic copolymer network may also be considered suitable for encapsulation of the water-soluble LMV within the hydrophilic component, as well as enabling its controlled delivery, and promotion of uptake by hepatic cells through incorporation of a lipophilic component.Author: Latavia Singh, Yahya E. Choonara, Lisa C. du Toit, Pradeep Kumar, Avirup Chakraborty, Viness Pillay
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