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https://onlinelibrary.wiley.com/doi/full/10.1002/bip.10585
Amphipathic peptides and drug delivery. Jimena Fernández‐Carneado. Institut de Recerca Biomèdica de Barcelona, Parc Científic de Barcelona, Josep Samitier 1–5, E‐08028 Barcelona, Spain. Departament de Química Orgànica, Universitat de Barcelona, Martí i Franqués 1–11, E‐08028 Barcelona, Spain.Author: Jimena Fernández-Carneado, Marcelo J. Kogan, Silvia Pujals, Ernest Giralt
https://www.ncbi.nlm.nih.gov/pubmed/15054899
Amphipathic peptides and drug delivery. Fernández-Carneado J(1), Kogan MJ, Pujals S, Giralt E. Author information: (1)Institut de Recerca Biomèdica de Barcelona, Parc Científic de Barcelona, Josep Samitier 1-5, E-08028 Barcelona, Spain.Author: Jimena Fernández-Carneado, Marcelo J. Kogan, Silvia Pujals, Ernest Giralt
https://www.researchgate.net/publication/8646112_Amphipathic_Peptides_and_Drug_Delivery
Amphipathic Peptides and Drug Delivery. ... Amphipathic peptides constitute a class of molecules with the potential to develop as efficient and safer alternative to viral and other non-viral ...
https://onlinelibrary.wiley.com/doi/abs/10.1002/bip.10585
Amphipathic peptides and drug delivery. Jimena Fernández‐Carneado ... The discovery of cell‐penetrating peptides as gene delivery systems and the interest in the mechanism by which these vectors cross the cell membrane have generated a large number of studies. ... studies and its interaction with the cell membrane result from our ...Author: Jimena Fernández-Carneado, Marcelo J. Kogan, Silvia Pujals, Ernest Giralt
https://pubs.acs.org/doi/10.1021/mp200481g
Cationic and amphipathic cell-penetrating peptides (CPPs): Their structures and in vivo studies in drug delivery. Frontiers of Chemical Science and Engineering 2015, 9 (4) , 407-427. DOI: 10.1007/s11705-015-1538-y. Anna Scomparin, Dina Polyak, Adva Krivitsky, Ronit Satchi-Fainaro.
https://pubs.acs.org/doi/10.1021/acsmedchemlett.6b00031
The promise of oligonucleotide therapeutic agents to perturb expression of disease-related genes remains unrealized, in part due to challenges with functional cellular delivery of these agents. Herein, we describe disulfide-constrained cyclic amphipathic peptides that complex with short-interfering RNA (siRNA) and affect functional cytosolic delivery and knockdown of target gene products in ...Author: Jade J. Welch, Ria J. Swanekamp, Christiaan King, David A. Dean, Bradley L. Nilsson
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6751769/
Drug-delivery systems (DDSs) based on endogenous lipid nanostructures, such ... thereby causing endosome destabilization and releasing the drug to the cytoplasm.30,31 FPL amphipathic peptides might also play a role in the endosome escape of FPLM NPs for the reason that they have the ability to insert into the endosome membrane and induce ...Author: Junyi Qian, Ningze Xu, Xu Zhou, Kaihong Shi, Qian Du, Xiaoxing Yin, Ziming Zhao
https://www.sciencedirect.com/science/article/pii/S0168365918303717
Overall, the number of papers related to the use of cell penetrating peptides for ocular drug delivery is still relatively low, but it has seen an exponential increase in the last 5 years, demonstrating the growing interest and expectations in this specific field. ... new amphipathic model peptides, deriving from substance P sequences, were ...Author: S. Pescina, C. Ostacolo, I.M. Gomez-Monterrey, M. Sala, A. Bertamino, F. Sonvico, C. Padula, P. Sant...
https://www.sciencedirect.com/science/article/pii/S0169409X98000052
This paper surveys several classes of these protein domains or peptides and the current hypotheses on their action. The possible impact of such membrane-destabilizing domains on intracellular drug delivery is reviewed. Ideally, small synthetic peptides should serve as membrane-active part of the drug …Author: Christian Plank, Wolfgang Zauner, Ernst Wagner
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