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https://patents.justia.com/assignee/alexza-molecular-delivery-corporation
Abstract: Devices and methods of entraining a substance within an airflow are disclosed. Condensation aerosol delivery devices and methods of consistently producing multiple doses of a substance, such as a drug, having high purity, high yield, characterized by a particle size distribution appropriate for pulmonary delivery, and which can be administered to a user in a single dose are also ...
https://www.ventureradar.com/organisation/Alexza%20Pharmaceuticals/17f9bad9-0380-4e1c-a792-dfec50187bb3
"Alexza Molecular Delivery Corporation is developing its own products using the company’s Staccato™ drug delivery technology. This enables the rapid onset of therapeutic effect of many small molecule drugs as well as patient self-titration to the lowest effective dose to improve the treatment of acute and intermittent conditions.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1884307/
Apr 19, 2002 · Pulmonary drug delivery offers several advantages as a route of administration for the treatment of systemic diseases compared with intravenous, oral, buccal, transdermal, vaginal, nasal or ocular administration. The advantages of pulmonary administration are listed in Table 1 [20–23]. Until recently, aerosol drug delivery has been limited to ...Author: N. R. Labiris, M. B. Dolovich
http://www.freepatentsonline.com/y2004/0101481.html
May 27, 2004 · Acute treatment of headache with phenothiazine antipsychotics ... Alexza Molecular Delivery Corporation (Palo Alto, CA, US) ... to a patient in aerosol form such that the patient inhales the composition by mouth or endotracheal tube in the pulmonary tract. “Administration by inhalation” does not include intranasal administration in this ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3276033/
Pulmonary drug delivery strategies: A concise, systematic review ... treatment of various chronic diseases a growing attention has been given to the development of targeted drug delivery systems. Pulmonary route of drug delivery gaining much importance in the present day research field as it enables to target the drug delivery directly to lung ...
https://patents.google.com/patent/CA2183577
CA2183577A1 CA 2183577 CA2183577A CA2183577A1 CA 2183577 A1 CA2183577 A1 CA 2183577A1 CA 2183577 CA2183577 CA 2183577 CA 2183577 A CA2183577 A CA 2183577A CA 2183577 A1 CA2183577 A1 CA 2183577A1 Authority CA Canada Prior art keywords insulin compositions methods pulmonary delivery dry Prior art date 1994-03-07 Legal status (The legal status is an …Author: John S. Patton, Linda C. Foster, Robert M. Platz
https://invivo.pharmaintelligence.informa.com/companies/200200760
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https://link.springer.com/article/10.1023/A:1016559707084
Jul 01, 2002 · Purpose. ABT-431 is a chemically stable, poorly soluble prodrug that rapidly converts in vivo to A-86929, a selective dopamine D-1 receptor agonist. This study was designed to evaluate the ability of the AERx™ pulmonary delivery system to deliver ABT …Author: Franklin W. Okumu, Rai-Yun Lee, James D. Blanchard, Anthony Queirolo, Christine M. Woods, Peter M. L...
http://www.freepatentsonline.com/y2004/0102434.html
May 27, 2004 · [0038] A preferred method of administration of loxapine and amoxapine, as a feature of the invention, is administration by inhalation, or pulmonary administration. Pulmonary drug delivery can be achieved by several different approaches, including liquid nebulizers, aerosol-based metered dose inhalers (MDI's), and dry powder dispersion devices.
http://www.pharmtech.com/pulmonary-drug-delivery-particle-engineering-inhaled-therapeutics
Feb 02, 2014 · Hovione: Pulmonary drug delivery is achieved through an understanding of the complex relationship between particle engineering, formulation and device. There are many goals for a formulation scientist when preparing a pulmonary drug-delivery system. First and …
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