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http://www.aradigm.com/docs/AERx%20Essence%ae%20Device%20Overview.pdf?lbisphpreq=1
The AERx® pulmonary delivery system combines precise control of aerosol particle size with regulation of the patient’s inhalation flow rate to achieve maximal efficiency of drug delivery to the lungs.
http://www.aradigm.com/technologies.html
Efficient, Precise Aerosol Generation Aradigm's AERx pulmonary drug delivery technology provides performance that is at the leading edge in terms of efficiency of delivery to the lung and reproducibility of dosing – not just in the laboratory but also as determined in many human clinical trials.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2751352/
The lung represents an attractive target for delivering gene therapy to achieve local and potentially systemic delivery of gene products. The objective of this study was to evaluate the feasibility of the AERx Pulmonary Delivery System for delivering nonviral gene therapy formulations to the lung.Author: Deepa Deshpande, James Blanchard, Sudarshan Srinivasan, Dallas Fairbanks, Jun Fujimoto, Teiji Sawa, ...
https://www.slideshare.net/sagarsavale1/pulmonary-drug-delivery-system-pdds
Jun 19, 2016 · The AERx Pulmonary Drug Delivery System 6/19/2016 Sagar kishor Savale 67. 67 • The AERx aerosol drug delivery system was developed to efficiently deliver topical and systemically active compounds to the lung in a way that is independent of such factors as user technique or …
https://www.sciencedirect.com/science/article/pii/S0168365997002605
The AERx™ pulmonary delivery system utilizes similar microprocessor capabilities; however, it employs a novel means of generating aqueous aerosols from unit dose packages, thus providing a broad inhalation technology base for delivery of a wide variety of therapeutic and diagnostic agents into the respiratory tract, and via the lung into the systemic circulation.Author: I Gonda, J.A Schuster, R.M Rubsamen, P Lloyd, D Cipolla, S.J Farr
https://www.researchgate.net/publication/11043502_Aerosolization_of_Lipoplexes_Using_AERx_R_Pulmonary_Delivery_System
Pulmonary drug delivery is an applied aerosol science, which facilitates the treatment of both lung and systemic disease.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3276033/
Pulmonary route of drug delivery gaining much importance in the present day research field as it enables to target the drug delivery directly to lung both for local and systemic treatment. Over the last 2 decades, the systemic absorption of a broad range of therapeutics after pulmonary application has been demonstrated in animals as well as in humans.
https://www.researchgate.net/publication/221843347_Pulmonary_drug_delivery_strategies_A_concise_systematic_review
Because of limitations associated with the conventional treatment of various chronic diseases a growing attention has been given to the development of targeted drug delivery systems. Pulmonary ...
https://www.pharmatutor.org/articles/pulmonary-drug-delivery-a-review
The delivery of the drug through the respiratory tract is called pulmonary drug delivery. In case of brochodialating drugs, this is advantageous as drug will deliver directly to region where its action is required so that the drug effect will be faster and low dose of drug can be administered through this delivery system and so the side effects can be decreased.
https://www.slideshare.net/ganapati123/pulmonary-drug-delivery-system1
Mar 18, 2013 · Metered dose inhalers (MDIs)Is a device that helps to deliver a specific amount of medication to the lungs.It is commonly used to treat asthma, chronic obstructive pulmonary disease (COPD).It is composed of 4 essential components.1.The base formulation- drug ,propellant,excipients.2.The container.3.Metering valve...
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