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https://www.researchgate.net/publication/7464265_Adjuvant_and_Antigen_Delivery_Properties_of_Virosomes
The most significant progress to date has been made with virosomes, a novel antigen delivery system that incorporates the haemagglutinin from influenza virus into liposomes and can induce both ...
http://www.eurekaselect.com/61478/article
Liposomes are one of the most intensively studied areas of vaccine and delivery system research. Several intrinsic features of liposomes lend themselves to their use in vaccines, particularly in terms of safety, versatility and adjuvant properties.Author: Reinhard Glück, Kelly Goodwin Burri, Ian Metcalfe
https://www.sciencedirect.com/topics/immunology-and-microbiology/virosome
Synthetic constructs, including liposomes, VLPs, virosomes, immune stimulating complexes, microparticles, and nanoparticles, are nonreplicating delivery systems that mimic live viruses in the way they appear to the immune system to enhance antigen delivery. They may also carry adjuvant.
https://www.immunology.org/public-information/bitesized-immunology/vaccines-and-therapeutics/adjuvants-particulate-antigen
Virosomes are very similar to liposomes but are based on viral membrane proteins to contribute to immunostimulation. Inclusion of viral membrane proteins such as haemagglutinin (Figure 1) exploits the targeting and fusogenic properties of this protein, perhaps improving the …
http://www.imedpub.com/articles/virosomes-as-a-drug-delivery-carrier.pdf
Virosomes: As a Drug Delivery Carrier Naresh Kalra *, V.Dhanya, Vineeta Saini, Dr. G. Jeyabalan Department of Pharmaceutics, Alwar Pharmacy College, IET, North extension MIA, Alwar. ABSTRACT Virosomes are reconstituted viral envelopes that can serve as vaccines and as vehicles for cellular delivery of various macromolecules.Author: Naresh Kalra, V. Dhanya, Vineeta Saini, G. Jeyabalan
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4534807/
Aug 12, 2015 · A major hurdle of developing successful and effective vaccines is to design antigen delivery systems in such a way that optimizes antigen presentation and induces broad protective immune responses. ... controllable and prolonged release properties, low toxicity, improved adjuvant and immunostimulatory properties - can be ... virosomes can be ...Author: Maria Trovato, Piergiuseppe De Berardinis
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3383374/
A potential advantage or application of this technology is to take advantage of the physical properties of virosomes, in terms of uptake by antigen presenting cells (APC), as well as the chemical composition, and compatibility with adjuvant molecules derived from lipid A.Author: Carl R Alving, Kristina K Peachman, Mangala Rao, Steven G Reed
https://www.sciencedirect.com/science/article/pii/S0958166904001430
In addition to HA-mediated cytoplasmic antigen delivery, IRIVs possess other features that contribute to their excellent adjuvant effect: first, APCs are targeted by the interaction of HA with sialic acid residues on the cell surface 23.••, 44.; second, the particle structure mediates …Author: Diana Felnerova, Jean-François Viret, Reinhard Glück, Christian Moser
https://www.researchgate.net/publication/286030583_Influenza_Virosomes_as_Antigen_Delivery_System
Influenza Virosomes as Antigen Delivery System. ... antigen carrier and adjuvant system for heterolo gous antigens. ... the biochemical and immunol ogical properties of virosomes were .
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