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https://www.researchgate.net/publication/12467817_Adeno-Associated_Viral_Vectors_as_a_Gene_Delivery_Vehicles_Review
Adeno-Associated Viral Vectors as a Gene Delivery Vehicles (Review) Article · Literature Review in International Journal of Molecular Medicine 6(1):17-27 · August 2000 with 22 Reads
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2835126/
Apr 30, 2009 · Gene therapy covers a broad spectrum of applications, from gene replacement and knockdown for genetic or acquired diseases such as cancer, to vaccination, each with different requirements for gene delivery. Viral vectors and synthetic liposomes have emerged as the vehicles of choice for many applications today, but both have limitations and ...Author: Yiqi Seow, Matthew J Wood
https://www.ncbi.nlm.nih.gov/pubmed/17406299
Construction of diverse adeno-associated viral libraries for directed evolution of enhanced gene delivery vehicles. Koerber JT(1), Maheshri N, Kaspar BK, Schaffer DV. Author information: (1)Department of Chemical Engineering and the Helen Wills Neuroscience Institute, University of California, Berkeley, California 94720-1462, USA.Author: James T Koerber, Narendra Maheshri, Brian K Kaspar, David V Schaffer
https://www.spandidos-publications.com/10.3892/ijmm.6.1.17/download
Adeno-associated virus (AAV) has recently emerged as an attractive vector for gene therapy. The inherent safety features of AAV-based vectors make them unique among other viral delivery systems. Although at least half of all adults are sero positive for antibodies against this human parvovirus (1),
http://www.nature.com/articles/gt2011151
Oct 13, 2011 · Vectors derived from adeno-associated virus (AAV) are currently the most promising vehicles for therapeutic gene delivery to the retina. Recently, subretinal administration of AAV2 has been ...Author: L H Vandenberghe, A Auricchio
https://www.nature.com/articles/nbt1182
Jan 22, 2006 · Adeno-associated viral vectors are highly safe and efficient gene delivery vehicles. However, numerous challenges in vector design remain, including neutralizing antibody responses, tissue ...Author: Narendra Maheshri, James T Koerber, Brian K Kaspar, David V Schaffer
https://www.sciencedirect.com/science/article/pii/S0024320520302988
Though non-viral vectors are safe for gene targeting, its low efficiency compared to viral vectors limits its application in cancer therapy . Research advancements along years made use of bacterial and viral vectors or the combination of these with synthetic carriers to overcome the drawbacks associated with the use of non-viral vectors alone.Author: Balamurugan Shanmugaraj, Lohanathan Bharathi Priya, B. Mahalakshmi, Shanmugam Subbiah, Rouh-Mei Hu, ...
https://www.researchgate.net/publication/255177933_Adeno-associated_Viruses_as_Liver-Directed_Gene_Delivery_Vehicles_Focus_on_Lipoprotein_Metabolism
Adeno-associated viral vectors have proven to be excellent gene delivery vehicles for somatic overexpression. These viral vectors can efficiently and selectively target the liver, which plays a ...
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