A Mouse Model For Adenovirus Gene Delivery

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A mouse model for adenovirus gene delivery

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC35442/
    Jul 03, 2001 · Here we describe a mouse model that facilitates efficient delivery of genes with Ad vectors. Transgenic B and T lymphocytes are now efficiently transduced with Ad. The stimulation with PMA of these lymphocytes was required to drive reporter gene expression from the cytomegalovirus (CMV) promoter of our Ad vectors.Author: Tiziano Tallone, Stephen Malin, Annika Samuelsson, Johannes Wilbertz, Mitsue Miyahara, Kensaku Okamo...

A mouse model for adenovirus gene delivery PNAS

    https://www.pnas.org/content/98/14/7910
    Jul 03, 2001 · Here we describe a mouse model that facilitates efficient delivery of genes with Ad vectors. Transgenic B and T lymphocytes are now efficiently transduced with Ad. The stimulation with PMA of these lymphocytes was required to drive reporter gene expression from the cytomegalovirus (CMV) promoter of our Ad vectors.Author: Tiziano Tallone, Stephen Malin, Annika Samuelsson, Johannes Wilbertz, Mitsue Miyahara, Kensaku Okamo...

A mouse model for adenovirus gene delivery - PNAS

    https://www.pnas.org/content/pnas/98/14/7910.full.pdf
    Jul 03, 2001 · The cellular attachment receptor for adenovirus (Ad), Coxsackie adenovirusreceptor(CAR),requiredfordeliveryofAdintoprimary cells, is not present on all cell types, thus restricting Ad-gene delivery systems. To circumvent this constrain, a transgenic mouse has been generated that expresses a truncated human CAR in all tissues analyzed.Author: Tiziano Tallone, Stephen Malin, Annika Samuelsson, Johannes Wilbertz, Mitsue Miyahara, Kensaku Okamo...

(PDF) A mouse model for adenovirus gene delivery

    https://www.researchgate.net/publication/11901933_A_mouse_model_for_adenovirus_gene_delivery
    The cellular attachment receptor for adenovirus (Ad), Coxsackie adenovirus receptor (CAR), required for delivery of Ad into primary cells, is not present on all cell types, thus restricting Ad-gene...

A mouse model for HIV-1 entry - PubMed Central (PMC)

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3465400/
    Sep 25, 2012 · Adenoviral Delivery of hCCR5-2A-hCD4. Recombinant adenoviruses provide an established tool for efficient gene delivery and expression (21, 22).To express high levels of the factors that restrict HIV entry in vivo, we used a recombinant human adenovirus (AdV) serotype 5 encoding hCCR5-2A-hCD4 under control of the CMV promoter (AdV-hCCR5-2A-hCD4) (21, 22) (Fig. 2A).Author: John Pietzsch, Henning Gruell, Stylianos Bournazos, Bridget M. Donovan, Florian Klein, Ron Diskin, M...

Comparison of Gene Delivery to the Kidney by Adenovirus ...

    https://www.liebertpub.com/doi/10.1089/hum.2019.127
    Dec 16, 2019 · Comparison of Gene Delivery to the Kidney by Adenovirus, Adeno-Associated Virus, and Lentiviral Vectors After Intravenous and Direct Kidney Injections. Jeffrey D. Rubin, Tien V. Nguyen, ... Mouse models that recapitulate a variety of human monogenic renal disorders such as nephrotic syndrome, Alport syndrome, and Bartter's syndrome, ...Author: Jeffrey D. Rubin, Tien V. Nguyen, Kari L. Allen, Katayoun Ayasoufi, Michael A. Barry

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