A Gastroretentive Floating Delivery System For 5-Fluorouracil

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(PDF) A gastro-retentive fl oating delivery system for 5 ...

    https://www.researchgate.net/publication/230877770_A_gastro-retentive_fl_oating_delivery_system_for_5-fl_uorouracil
    A gastro-retentive fl oating delivery system for 5-fl uorouracil Article (PDF Available) in Asian Journal of Pharmaceutical Sciences 2(4):143-149 · September 2007 with 192 Reads How we measure ...

FORMULATION AND EVALUATION OF STOMACH – SPECIFIC …

    http://ijpsr.com/bft-article/formulation-and-evaluation-of-stomach-specific-novel-gastro-retentive-formulations-of-5-fluorouracil-for-targeting-gastric-cancer/?view=fulltext
    The tablet hardness was maintained in the range of 5 - 6 kg/cm 2. Evaluation of the Prepared Tablets: All the tablets were evaluated for core tablet properties (hardness, friability, weight variation, thickness, and content uniformity), floating behaviour,...

A 5-fluorouracil-loaded floating gastroretentive hollow ...

    https://www.dovepress.com/a-5-fluorouracil-loaded-floating-gastroretentive-hollow-microsphere-de-peer-reviewed-fulltext-article-DDDT
    Oct 06, 2015 · These results suggested that the hollow microspheres would be a promising controlled drug delivery system for an oral chemotherapy agent like 5-FU. Keywords: hollow microspheres, polyvinyl pyrrolidone, ethyl cellulose, pharmacokinetics, distribution, 5-fluorouracil

(PDF) Gastroretentive Floating Drug-Delivery Systems: A ...

    https://www.researchgate.net/publication/50373742_Gastroretentive_Floating_Drug-Delivery_Systems_A_Critical_Review
    Aim The aim of this study was to design a gastroretentive drug delivery system for controlled delivery of ciprofloxacin using Chrysophyllum albidum gum (CAG) in combination with hydrophilic ...

Gastroretentive Floating and Mucoadhesive Drug Delivery ...

    http://iosrjournals.org/iosr-jpbs/papers/Vol11-issue3/Version-1/N1103018996.pdf
    Abstract: Gastro retentive drug delivery system (GRDDS) is one of the novel approaches in the area of oral sustained release dosage forms. Drugs that are easily absorbed from gastrointestinal tract …File Size: 364KB

Gastro retentive Drug Delivery System: A Review

    https://ijpras.com/storage/models/article/TeYOGN6dBciE6RSaYCvW8hR2FcFAQVag5S1dwxVGo5yZrYaTt4UG4Qf5nKWQ/gastroretentive-drug-delivery-system-a-review.pdf
    such drug delivery system. Floating drug delivery system has a bulk density lower than gastric fluids and thus remain buoyant in the stomach for prolong period of time, without affecting the gastric emptying rate. While the system is floating on the gastric content, the drug is released slowly at a desired rate from the stomach.

FLOATING DRUG DELIVERY SYSTEM - AN APPROACH FOR ...

    http://www.ijpacr.com/files/25-8-18/03.pdf
    Floating drug delivery system (FDDS) provides local delivery of the drug to specific region of stomach and proximal part of small intestine and also shows a better bioavailability and improved therapeutic efficacy and hence a significant benefits to the patients.

Floating Drug Delivery System - IJPRAS

    https://ijpras.com/storage/models/article/OhRhPLbWg4mpuS1jZoRqHvFkFShoKdJ1jZfzavWSr3JrVa8B48dMmCyYtY0j/floating-drug-delivery-system.pdf
    fluids. Floating drug delivery system (FDDS) have a bulk density less than gastric fluids and so remain buoyant in the stomach without affecting the gastric emptying rate for a prolonged period of time (Yie W. Chein et al, 1992). While the system is floating on the gastric contents, the drug is released slowly at the desired rate from the system.

Review Article FLOATING DRUG DELIVERY SYSTEM

    https://www.ijrdpl.com/uploads/41/1846_pdf.pdf
    The aim of writing this review on gastro retentive and floating drug delivery system was to compile the new literature with the principle mechanism of floatation to acquired gastric retention. Various attempts have been made to develop gastroretentive delivery systems such as high density system, swelling, floating system.

Gastroretentive drug delivery systems.

    https://www.ncbi.nlm.nih.gov/pubmed/16506949
    A controlled drug delivery system with prolonged residence time in the stomach is of particular interest for drugs that i) are locally active in the stomach, ii) have an absorption window in the stomach or in the upper small intestine, iii) are unstable in the intestinal or colonic environment, or iv) exhibit low solubility at high pH values.Author: Alexander Streubel, Juergen Siepmann, Roland Bodmeier

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