We have collected information about A Family Of Bioreducible Polymers For Gene Delivery for you. Follow the links to find out details on A Family Of Bioreducible Polymers For Gene Delivery.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2737532/
A Family of Bioreducible Poly(disulfide amine)s for Gene Delivery Mei Ou , a Rongzuo Xu , a Sun Hwa Kim , b David A. Bull , c and Sung Wan Kim a, * a Department of Pharmaceutics and Pharmaceutical Chemistry, University of Utah, Salt Lake City, Utah 84112Author: Mei Ou, Rongzuo Xu, Sun Hwa Kim, David A. Bull, Sung Wan Kim
https://www.sciencedirect.com/science/article/pii/S014296120900653X
We have synthesized and evaluated a family of bioreducible poly(disulfide amine)s as polymeric gene vectors. The incorporation of multiple functional groups, such as amine groups and disulfide bonds, gives these cationic polymers good DNA condensation ability, protonation ability, charge density, buffering capacity and intracellular biodegradability.Author: Mei Ou, Rongzuo Xu, Sun Hwa Kim, David A. Bull, Sung Wan Kim
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3079258/
Mar 01, 2011 · Bioreducible polymers, which possess mainly disulfide linkages in the polymer structures, have appeared as ideal gene delivery carriers due to the high stability in extracellular physiological condition and bioreduction-triggered release of genetic materials, as well as decreased cytotoxicity because intracellular cytosol is a reducing environment containing high level of reducing molecules …Author: Tae Il Kim, Sung Wan Kim, Sung Wan Kim
https://www.researchgate.net/publication/26679589_A_Family_of_Bioreducible_Polydisulfide_amines_for_Gene_Delivery
Bioreducible polymers have attracted intense attention as a gene carrier due to their low cell toxicity compared to other polymer-based gene delivery counterparts.
https://www.sciencedirect.com/science/article/pii/S1381514810002117
Bioreducible polymers, which possess mainly disulfide linkages in the polymer structures, have appeared as ideal gene delivery carriers due to the high stability in extracellular physiological condition and bioreduction-triggered release of genetic materials, as well as decreased cytotoxicity because intracellular cytosol is a reducing environment containing high level of reducing molecules such as …Author: Tae Il Kim, Sung Wan Kim, Sung Wan Kim
https://pubs.acs.org/doi/10.1021/ar200248u
Among the numerous multifunctional polymers that have been designed and evaluated as gene delivery vectors, polymers with redox-sensitive (or bioreducible) functional domains have gained great attention in terms of their structural and functional traits.Author: Sejin Son, Ran Namgung, Jihoon Kim, Kaushik Singha, Won Jong Kim
https://www.sciencedirect.com/science/article/pii/S016836591400220X
The works described in this review demonstrate current advances in the field of non-viral bioreducible polymers for therapeutic gene delivery to cardiovascular disease, anemia, diabetes, and cancer. The smart and advanced chemical modifications of bioreducible polymers will accelerate their progress toward human clinical application.Author: Young Sook Lee, Sung Wan Kim, Sung Wan Kim
https://www.researchgate.net/publication/51073220_Bioreducible_polymers_for_gene_delivery
Bioreducible polymers, which possess mainly disulfide linkages in the polymer structures, have appeared as ideal gene delivery carriers due to the high stability in extracellular physiological...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4142085/
Sep 28, 2014 · The works described in this review demonstrate current advances in the field of non-viral bioreducible polymers for therapeutic gene delivery to cardiovascular disease, anemia, diabetes, and cancer. The smart and advanced chemical modifications of bioreducible polymers will accelerate their progess toward human clinical application.Author: Young Sook Lee, Sung Wan Kim, Sung Wan Kim
https://www.nature.com/articles/nrd1775
Jul 01, 2005 · The lack of safe and efficient gene-delivery methods is a limiting obstacle to human gene therapy. Synthetic gene-delivery agents, although safer …Author: Daniel W. Pack, Allan S. Hoffman, Suzie Pun, Patrick S. Stayton
Searching for A Family Of Bioreducible Polymers For Gene Delivery?
You can just click the links above. The data is collected for you.
