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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3011081/
The aim of this study is to develop a buccal tablet for the delivery of a poorly water-soluble drug. The chosen model drug is omeprazole (OME), a proton pump inhibitor in gastric parietal cells (16,17).Author: Ana Figueiras, Alberto A. C. C. Pais, Francisco J. B. Veiga
https://www.ncbi.nlm.nih.gov/pubmed/21116750
According to these results, the system containing the selected polymer mixture and the drug complexed with methyl-β-cyclodextrin in presence of L: -arginine showed a great potential as a buccal drug delivery formulation, in which a good compromise among mucoadhesion, dissolution, and permeation properties was achieved.Author: Ana Figueiras, Alberto A. C. C. Pais, Francisco J. B. Veiga
https://link.springer.com/article/10.1208/s12249-010-9546-1
Nov 30, 2010 · The feasibility of drug buccal administration was assessed by permeation experiments on porcine buccal mucosa. The amount of drug permeated from mucoadhesive tablets presented a maximum value for the system containing drug complexed with the methylated cyclodextrin derivative in presence of l-arginine.Author: Ana Figueiras, Alberto A. C. C. Pais, Francisco J. B. Veiga
https://core.ac.uk/display/8505908
The feasibility of drug buccal administration was assessed by permeation experiments on porcine buccal mucosa. The amount of drug permeated from mucoadhesive tablets presented a maximum value for the system containing drug complexed with the …
https://www.marketwatch.com/press-release/buccal-drug-delivery-systems-market-2019-size-global-trends-comprehensive-research-study-development-status-opportunities-future-plans-competitive-landscape-and-growth-by-forecast-2025-2020-02-14
Feb 14, 2020 · The report hints at crucial information associated with new market developments being undertaken in the Buccal Drug Delivery Systems industry before …
https://tginnovations.wordpress.com/2014/05/07/buccal-drug-delivery-systems/
May 07, 2014 · Drug delivery through various mucosal surfaces may improve bioavailability by bypassing the first-pass effects and avoiding the elimination of the drug within the gastrointestinal (GI) tract. Transmucosal drug delivery is being considered as an attractive delivery route for new and existing drug compounds, some of which are only available today through parenteral delivery.
https://www.sciencedirect.com/science/article/pii/S1740674905000235
The strategies studied to overcome such obstacles include the employment of new materials that, possibly, combine mucoadhesive, enzyme inhibitory and penetration enhancer properties and the design of innovative drug delivery systems which, besides improving patient compliance, favor a more intimate contact of the drug with the absorption mucosa.Author: Silvia Rossi, Giuseppina Sandri, Carla M. Caramella
https://drug-dev.com/buccal-delivery-dissolvable-film-format-evolves-to-buccal-drug-delivery-applications/
In the case of buccal applications, it is up to the product designer to determine at what point the thickness or overall size of the buccal drug delivery device becomes unacceptable to the patient. Because there is a limitation in the size of the final buccal product, typically 1 to 5 square centimeters, this limited surface area dictates that the APIs must be fairly potent.
https://jnanobiotechnology.biomedcentral.com/articles/10.1186/s12951-018-0392-8
Sep 19, 2018 · Liposomes are an engrained formulation strategy to improve the drug delivery. They are vesicles of spherical form composed of phospholipids and steroids usually in …Author: Jayanta Kumar Patra, Gitishree Das, Leonardo Fernandes Fraceto, Leonardo Fernandes Fraceto, Estefani...
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