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https://en.wikipedia.org/wiki/Paracetamol
Paracetamol, also known as acetaminophen, is a medication used to treat fever and mild to moderate pain. At a standard dose, paracetamol only slightly decreases body temperature; it is inferior to ibuprofen in that respect, and the benefits of its use for fever are unclear. Paracetamol may relieve pain in acute mild migraine but only slightly in episodic tension headache.
https://www.drugs.com/paracetamol.html
Feb 16, 2021 · >=12 years: 325 to 650 mg every 4 to 6 hours or 1000 mg every 6 to 8 hours. Usual Pediatric Dose for Pain: Oral or Rectal: <=1 month: 10 to 15 mg/kg/dose every 6 to 8 hours as needed. >1 month to 12 years: 10 to 15 mg/kg/dose every 4 to 6 hours as needed (Maximum: 5 doses in 24 hours)
https://en.wikipedia.org/wiki/Paracetamol_poisoning
Paracetamol poisoning, also known as acetaminophen poisoning, is caused by excessive use of the medication paracetamol (acetaminophen). Most people have few or non-specific symptoms in the first 24 hours following overdose. These include feeling tired, abdominal pain, or nausea.This is typically followed by a couple of days without any symptoms, after which yellowish skin, blood clotting ...
https://litfl.com/paracetamol-toxicity/
Nov 03, 2020 · The threshold for potential paracetamol-induced hepatic injury in adults is >10g or >200 mg/kg (whichever is less) within 24 hours. So, 10g is the toxic dose for all those heavier than 50kg.
https://www.thelancet.com/journals/eclinm/article/PIIS2589-5370(19)30066-5/fulltext
May 02, 2019 · At the end of the 12 h SNAP regimen blood samples were taken for liver function, creatinine, INR and paracetamol concentration; if these blood tests were less than 24 h after the last dose of paracetamol, the blood tests were repeated at 24 h.
https://www.mims.com/malaysia/drug/info/paracetamol
After 12-48 hours of ingestion, liver damage may become apparent, which may lead to encephalopathy, haemorrhage, hypoglycaemia, hypotension, cerebral oedema, cardiac arrhythmia, and pancreatitis. Management: Administer activated charcoal within 1 hour of ingestion. Determine plasma paracetamol concentration ≥4 hours after ingestion.
https://www.medicinehow.com/paracetamol/
Most of these brands come in a tablet form, with 500 mg of paracetamol in each tablet. For adults over the age of 12 years, the standard dose is 0.5-1 g (1-2 tablets) every 4-6 hours. The maximum dose that an adult should have in any 24-hour period is 4 g (or 8 tablets).
https://www.ncbi.nlm.nih.gov/books/NBK501194/
Oct 31, 2018 · Acetaminophen was undetectable (<0.5 mg/L) in all mothers 12 hours after the dose. The authors calculated that an infant who ingested 90 mL of breastmilk every 3 hours would receive an average of 0.88 mg of acetaminophen or 0.14% (range 0.04 …
https://www.omnicalculator.com/health/paracetamol-dosage
Mar 03, 2021 · Paracetamol dosage for children by weight. The regularly prescribed analgesic and antipyretic oral or rectal dose of paracetamol for children over 3 months is. 10 to 15 mg per 1 kilogram of body weight. It can be administered every 4 to 6 hours, with a maximum of 5 doses in 24 hours. The maximal daily pediatric dose of paracetamol is. 60 mg/kg
https://www.healthdirect.gov.au/paracetamol
The recommended dose of paracetamol for adults and children 12 years and over is no more than 1g every 4-6 hours to a total of 4g daily. The maximum dose for children is dependent on their body weight. The labels on liquid paracetamol contain clear instructions.
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