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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3003827/
3M’s hMTS can provide rapid, intradermal delivery of 300–1,500 µL of liquid formulations of small molecules salts and proteins, compounds not typically compatible with passive transdermal delivery.Author: Scott A. Burton, Chin-Yee Ng, Ryan Simmers, Craig Moeckly, David Brandwein, Tom Gilbert, Nathan John...
https://www.3m.com/3M/en_US/drug-delivery-systems-us/technologies/transdermal/
Help to differentiate your product in today's competitive market by leveraging 3M’s expertise in adhesive and polymer science, applied to providing a comprehensive transdermal drug delivery offering from start to finish. With the breadth of 3M resources, we offer dedicated customer service and reliable quality to enable customer success.
https://www.3mindia.in/3M/en_IN/drug-delivery-systems-in/technologies/microneedle/hollow-needle/
Differentiate your product with 3M™ Hollow Microstructured Transdermal System for intradermal delivery of biologics. 3M Hollow Microstructured Transdermal System offers reproducible intradermal delivery, and provides a patient-friendly design based on human factors testing and voice-of …
http://news.3m.com/press-release/company/microneedles-breakthrough-brings-3m-one-step-closer-introducing-new-alternativ
"3M™ Hollow Microstructured Transdermal System continues to demonstrate a number of unique benefits, including reproducible intradermal delivery, a proven ability to deliver formulations up to 2 mL with various viscosities, and API-dependent PK profile benefits"
https://www.ttp.com/work/cases/ttp-designs-commercial-ready-applicator-for-3ms-hollow-microneedle-array
TTP worked with 3M to develop their hollow microstructured transdermal system (hMTS) into a device for convenient self-administration of liquid drug formulations. By providing reliable intradermal drug delivery, this offers the possibility of faster drug action and improved bioavailability over existing subcutaneous delivery methods.
https://link.springer.com/article/10.1007%2Fs11095-010-0177-8
Jun 26, 2010 · The purpose of this work is to demonstrate rapid intradermal delivery of up to 1.5 mL of formulation using a hollow microneedle delivery device designed for self-application. 3M’s hollow Microstructured Transdermal System (hMTS) was applied to domestic swine to demonstrate delivery of a variety of formulations including small molecule salts and proteins.
https://www.3m.com/3M/en_US/drug-delivery-systems-us/resources/news/news-detail/?storyid=a9d79d86-f599-45a9-85c6-235d5a9a34cf
3M Drug Delivery Systems announces a new phase of an ongoing collaboration with Panacea Pharmaceuticals, Inc. in delivering an investigational therapeutic cancer vaccine directly to the dermis via the 3M™ Hollow Microstructured Transdermal System (hMTS).
https://www.3m.com/3M/en_US/drug-delivery-systems-us/technologies/microneedle/solid/
Solid microneedle technology relies on tiny needles mounted on a wearable patch to deliver proteins vaccines or other solid formulations up to 300 mcg. By reducing anxiety associated with vaccinations or other injections, solid microneedle technology from 3M may help improve patient compliance and overall treatment outcome.
https://multimedia.3m.com/mws/media/1023004O/hmts-3-step-feasibility-leaflet-january-2015.pdf
3M Hollow Microstructured Transdermal System Now available for feasibility and clinical studies! Would your biologic bene t from intradermal delivery? Did you know...
http://pharmaedresources.com/brochures/Transdermal2017.pdf
scope of transdermal delivery to include hydrophilic macromolecules • Learn the success and failures of novel skin delivery technologies developed and marketed over the years. 8:55 Keynote: Recent Advancements in Intradermal Delivery of Biopharmaceuticals Lisa Dick, Ph.D., Lab Manager & Technology Leader, 3M Drug Delivery Systems
https://www.nature.com/articles/s41467-019-08852-4
Intradermal VEGF-A mRNA was well tolerated and led to local functional VEGF-A protein expression and transient skin blood flow enhancement in men with T2DM. ... Intradermal delivery of modified ...
https://www.3mindia.in/3M/en_IN/drug-delivery-systems-in/technologies/microneedle/
3M Microneedle Drug Delivery Systems, which include Hollow Microneedle and Solid Microneedle technology, offer patient-friendly delivery solutions for vaccines or difficult-to-deliver biologics for particularly needle-phobic patients. By potentially reducing anxiety, microneedle delivery may improve patient compliance in some patient groups.
https://www.ondrugdelivery.com/innovative-drug-delivery-technology-meet-evolving-need-biologics-small-molecules/
Delivery of the formulation through hollow microneedles is powered by a mechanical spring. A combination of drug and 3M Hollow Microstructured Transdermal System provides a fully integrated delivery device designed for reproducible intradermal delivery of liquid formulations.
https://www.ondrugdelivery.com/wp-content/uploads/2017/05/1060_GF_ONdrgDelivery_Issue-56_-transdermal_MR.pdf
3M DRUG DELIVERY SYSTEMS We put no limits on curiosity Microneedle Transdermal Inhalation Oral & ... System is designed for intradermal delivery of liquid formulations, including biologics, such as proteins and peptides, in addition to small molecules. Hollow microneedles have
http://www.biopharminternational.com/optimizing-unique-cancer-vaccine-intradermal-delivery
Sep 15, 2017 · Optimizing a Unique Cancer Vaccine for Intradermal Delivery. ... 3M Drug Delivery Systems and Panacea Pharmaceuticals are collaborating to deliver Panacea’s investigational cancer vaccine, PAN- 301-1, directly to the dermis via the 3M hollow microstructured transdermal system (hMTS). ... "Optimizing a Unique Cancer Vaccine for Intradermal ...
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